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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ID2 All Species: 17.48
Human Site: S129 Identified Species: 42.74
UniProt: Q02363 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02363 NP_002157.2 134 14917 S129 S E L M S N D S K A L C G _ _
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001110458 154 16013 A140 G E I S A L T A E A A C V P T
Dog Lupus familis XP_852210 203 21022 A189 G E I S A L A A E A A C V P A
Cat Felis silvestris
Mouse Mus musculus P41136 134 14941 S129 S E L M S N D S K V L C G _ _
Rat Rattus norvegicus P41137 134 14971 S129 S E L M S N D S K V L C G _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509293 134 14845 S129 S E L M S S D S K A L C G _ _
Chicken Gallus gallus NP_990333 134 14780 S129 S E L M A S D S K A L C G _ _
Frog Xenopus laevis NP_001081902 133 14786
Zebra Danio Brachydanio rerio NP_958448 137 15209
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P18491 199 21960 N129 D I L A Q R L N A E Q P A K V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 41.5 32 N.A. 98.5 97.7 N.A. 94.7 94 80.5 78 N.A. 24.1 N.A. N.A. N.A.
Protein Similarity: 100 N.A. 60.3 48.2 N.A. 99.2 98.5 N.A. 97 98.5 88.8 85.4 N.A. 37.1 N.A. N.A. N.A.
P-Site Identity: 100 N.A. 20 20 N.A. 92.3 92.3 N.A. 92.3 84.6 0 0 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 46.6 46.6 N.A. 92.3 92.3 N.A. 100 100 0 0 N.A. 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 30 0 10 20 10 50 20 0 10 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 70 0 0 0 % C
% Asp: 10 0 0 0 0 0 50 0 0 0 0 0 0 0 0 % D
% Glu: 0 70 0 0 0 0 0 0 20 10 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 20 0 0 0 0 0 0 0 0 0 0 0 50 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 20 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 50 0 0 0 0 10 0 % K
% Leu: 0 0 60 0 0 20 10 0 0 0 50 0 0 0 0 % L
% Met: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 30 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 10 0 20 0 % P
% Gln: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % R
% Ser: 50 0 0 20 40 20 0 50 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 0 0 0 20 0 0 20 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 50 50 % _