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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SP4 All Species: 15.76
Human Site: T37 Identified Species: 38.52
UniProt: Q02446 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02446 NP_003103.2 784 81985 T37 N N N K K P K T S G S Q D S Q
Chimpanzee Pan troglodytes Q19A40 323 33082
Rhesus Macaque Macaca mulatta XP_001101092 866 90913 T119 N N N K K P K T S G S Q D S Q
Dog Lupus familis XP_539462 788 82259 T41 N N N K K P K T S G S Q D S Q
Cat Felis silvestris
Mouse Mus musculus Q62445 782 81947 T35 N N N K K P K T S G S Q D S Q
Rat Rattus norvegicus Q01714 786 80753 F35 G N G G G A A F S Q T R S S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514802 816 85651 K44 P A P E K P V K Q E E M A A L
Chicken Gallus gallus Q90WR8 771 80932 S35 Q H G N G N A S A S A A A A A
Frog Xenopus laevis NP_001083425 767 80109 T36 P L A L L A A T C S K I G T T
Zebra Danio Brachydanio rerio NP_956418 714 74632
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 21.9 90.1 97.9 N.A. 97.3 38.7 N.A. 35.5 41.5 80.9 61.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 26.9 90.1 98.3 N.A. 98 54.8 N.A. 51.3 58.4 88.5 73.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 0 100 100 N.A. 100 20 N.A. 13.3 0 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 0 100 100 N.A. 100 33.3 N.A. 26.6 33.3 13.3 0 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 0 20 30 0 10 0 10 10 20 20 10 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 40 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 10 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 10 0 20 10 20 0 0 0 0 40 0 0 10 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 40 50 0 40 10 0 0 10 0 0 0 0 % K
% Leu: 0 10 0 10 10 0 0 0 0 0 0 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 40 50 40 10 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 20 0 10 0 0 50 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 10 10 0 40 0 0 40 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 10 50 20 40 0 10 50 10 % S
% Thr: 0 0 0 0 0 0 0 50 0 0 10 0 0 10 10 % T
% Val: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _