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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DSC2
All Species:
12.73
Human Site:
T760
Identified Species:
31.11
UniProt:
Q02487
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02487
NP_004940.1
901
99962
T760
A
N
G
F
T
T
Q
T
V
G
A
S
A
Q
G
Chimpanzee
Pan troglodytes
XP_512077
943
103977
T802
A
N
G
F
T
T
Q
T
V
G
A
S
T
Q
G
Rhesus Macaque
Macaca mulatta
XP_001102096
954
105079
T813
A
N
G
F
T
T
Q
T
V
G
A
S
A
Q
G
Dog
Lupus familis
XP_866930
902
100740
T761
T
D
G
F
T
T
H
T
V
G
S
S
A
Q
G
Cat
Felis silvestris
Mouse
Mus musculus
P55292
902
99943
M761
N
G
L
T
T
Q
T
M
G
A
S
G
Q
T
A
Rat
Rattus norvegicus
Q9Z1Y3
906
99668
R767
I
D
P
E
D
D
V
R
D
N
I
L
K
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515354
1013
112098
D872
G
P
G
E
E
V
M
D
A
N
I
R
L
P
N
Chicken
Gallus gallus
P24503
913
100867
R774
I
D
P
E
D
D
V
R
D
N
I
L
K
Y
D
Frog
Xenopus laevis
P79883
922
101155
D780
Q
L
L
I
D
P
E
D
D
V
R
D
N
I
L
Zebra Danio
Brachydanio rerio
Q90275
893
98972
P749
A
K
Q
L
L
I
D
P
E
D
D
V
R
D
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
91.3
81.8
N.A.
75.7
32.6
N.A.
50.6
30.8
31.5
32.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
94.8
92.6
90
N.A.
86.5
50.4
N.A.
65.6
49.9
49.1
50.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
100
73.3
N.A.
6.6
0
N.A.
6.6
0
0
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
100
86.6
N.A.
13.3
6.6
N.A.
6.6
6.6
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
0
0
0
0
0
0
10
10
30
0
30
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
30
0
0
30
20
10
20
30
10
10
10
0
10
20
% D
% Glu:
0
0
0
30
10
0
10
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
10
50
0
0
0
0
0
10
40
0
10
0
0
40
% G
% His:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
20
0
0
10
0
10
0
0
0
0
30
0
0
10
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
20
0
0
% K
% Leu:
0
10
20
10
10
0
0
0
0
0
0
20
10
0
10
% L
% Met:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% M
% Asn:
10
30
0
0
0
0
0
0
0
30
0
0
10
0
20
% N
% Pro:
0
10
20
0
0
10
0
10
0
0
0
0
0
10
0
% P
% Gln:
10
0
10
0
0
10
30
0
0
0
0
0
10
40
0
% Q
% Arg:
0
0
0
0
0
0
0
20
0
0
10
10
10
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
20
40
0
0
0
% S
% Thr:
10
0
0
10
50
40
10
40
0
0
0
0
10
10
0
% T
% Val:
0
0
0
0
0
10
20
0
40
10
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _