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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HIST1H1A All Species: 25.45
Human Site: S54 Identified Species: 62.22
UniProt: Q02539 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02539 NP_005316.1 215 21842 S54 I V Q A A S S S K E R G G V S
Chimpanzee Pan troglodytes XP_527252 215 21792 S54 I V Q A A S S S K E R G G V S
Rhesus Macaque Macaca mulatta P40286 208 22075 S53 K L I T E A L S V S Q E R V G
Dog Lupus familis XP_545380 215 21790 S54 I V Q A V S S S K E R S G V S
Cat Felis silvestris
Mouse Mus musculus P43276 223 22558 S51 I T K A V S A S K E R G G V S
Rat Rattus norvegicus P15865 219 21969 S51 I T K A V A A S K E R S G V S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515094 223 22581 S51 I T K A V S V S K E R N G V S
Chicken Gallus gallus P08284 219 22026 S52 I T K A V S A S K E R K G L S
Frog Xenopus laevis P06892 210 21355 S55 E Q I V T A V S A S K E R S G
Zebra Danio Brachydanio rerio XP_002667660 183 19011 H28 V T A S K E R H G V S L A A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 51.6 82.3 N.A. 68.6 70.7 N.A. 68.6 64.8 53.9 54.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 64.1 87.4 N.A. 73.5 77.1 N.A. 78 72.5 64.6 64.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 13.3 86.6 N.A. 73.3 60 N.A. 66.6 60 6.6 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 86.6 N.A. 86.6 80 N.A. 73.3 80 20 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 70 20 30 30 0 10 0 0 0 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 10 0 0 0 10 10 0 0 0 70 0 20 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 10 0 0 30 70 0 20 % G
% His: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 70 0 20 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 40 0 10 0 0 0 70 0 10 10 0 0 0 % K
% Leu: 0 10 0 0 0 0 10 0 0 0 0 10 0 10 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 10 30 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 70 0 20 0 0 % R
% Ser: 0 0 0 10 0 60 30 90 0 20 10 20 0 10 70 % S
% Thr: 0 50 0 10 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 10 30 0 10 50 0 20 0 10 10 0 0 0 70 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _