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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IRF8
All Species:
25.45
Human Site:
S230
Identified Species:
62.22
UniProt:
Q02556
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02556
NP_002154.1
426
48356
S230
C
P
E
G
C
R
L
S
L
S
Q
P
G
L
P
Chimpanzee
Pan troglodytes
XP_511152
436
49336
S240
C
P
E
G
C
R
L
S
L
S
Q
P
G
L
P
Rhesus Macaque
Macaca mulatta
XP_001084409
426
48303
S230
C
P
E
G
C
R
L
S
L
S
Q
P
G
L
P
Dog
Lupus familis
XP_546793
426
48688
S230
C
P
E
G
C
R
L
S
L
S
Q
P
G
L
P
Cat
Felis silvestris
Mouse
Mus musculus
P23611
424
48219
S230
C
L
E
G
C
R
L
S
L
S
Q
P
G
L
P
Rat
Rattus norvegicus
P23570
328
37046
T165
P
D
D
H
S
S
Y
T
A
Q
G
Y
L
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507292
427
49638
S231
Y
P
E
G
C
R
I
S
L
N
Q
P
P
M
H
Chicken
Gallus gallus
Q90871
425
49152
S232
Y
P
E
G
C
R
L
S
L
S
Q
P
S
N
H
Frog
Xenopus laevis
NP_001087097
411
47602
P229
I
S
V
A
Q
H
L
P
G
A
E
N
F
E
N
Zebra Danio
Brachydanio rerio
NP_001002622
423
48376
L227
G
C
R
I
S
P
C
L
P
S
T
A
N
G
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.4
98.8
91.7
N.A.
89.6
24.1
N.A.
79.6
73.7
64.3
55.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.7
99
94.8
N.A.
93.1
39.9
N.A.
90.4
85.4
78.4
71.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
60
73.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
80
73.3
20
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
10
10
0
10
0
0
0
% A
% Cys:
50
10
0
0
70
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
70
0
0
0
0
0
0
0
10
0
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% F
% Gly:
10
0
0
70
0
0
0
0
10
0
10
0
50
20
0
% G
% His:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
20
% H
% Ile:
10
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
0
0
70
10
70
0
0
0
10
50
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
10
0
10
10
10
10
% N
% Pro:
10
60
0
0
0
10
0
10
10
0
0
70
10
0
50
% P
% Gln:
0
0
0
0
10
0
0
0
0
10
70
0
0
0
10
% Q
% Arg:
0
0
10
0
0
70
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
10
0
0
20
10
0
70
0
70
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
20
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _