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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NHLH1
All Species:
20
Human Site:
S62
Identified Species:
44
UniProt:
Q02575
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02575
NP_005589.1
133
14618
S62
R
K
D
L
Q
H
L
S
R
E
E
R
R
R
R
Chimpanzee
Pan troglodytes
Q8MI03
201
20743
G83
K
K
S
A
G
C
G
G
G
G
G
G
G
A
G
Rhesus Macaque
Macaca mulatta
XP_001117555
133
14630
S62
R
K
D
M
Q
H
L
S
R
E
E
R
R
R
R
Dog
Lupus familis
XP_545756
132
14498
S61
R
K
D
L
Q
H
L
S
R
E
E
R
R
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q02576
133
14811
S62
R
K
D
L
Q
H
L
S
R
E
E
R
R
R
R
Rat
Rattus norvegicus
Q66HH3
278
29939
E136
K
R
R
P
S
H
G
E
L
D
L
V
D
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514480
139
15024
S68
Y
P
H
P
Q
Q
L
S
R
E
E
K
R
R
R
Chicken
Gallus gallus
P24899
311
33749
P96
G
E
A
M
Q
R
A
P
G
A
E
P
C
R
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_476989
167
18981
S95
P
S
E
L
V
G
L
S
R
E
E
R
R
R
R
Honey Bee
Apis mellifera
XP_001122281
93
10416
R30
R
E
E
R
R
R
R
R
R
A
T
Q
K
Y
R
Nematode Worm
Caenorhab. elegans
NP_508440
89
10539
R26
S
K
A
E
R
R
K
R
R
R
A
T
P
K
Y
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
26.3
98.5
94.7
N.A.
92.4
23.3
N.A.
66.1
23.1
N.A.
N.A.
N.A.
46.1
57.8
45.8
N.A.
Protein Similarity:
100
38.8
99.2
95.4
N.A.
92.4
29.1
N.A.
71.2
29.2
N.A.
N.A.
N.A.
53.8
61.6
57.1
N.A.
P-Site Identity:
100
6.6
93.3
100
N.A.
100
6.6
N.A.
60
20
N.A.
N.A.
N.A.
66.6
20
13.3
N.A.
P-Site Similarity:
100
13.3
100
100
N.A.
100
26.6
N.A.
66.6
33.3
N.A.
N.A.
N.A.
73.3
53.3
26.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
10
0
0
10
0
0
19
10
0
0
10
10
% A
% Cys:
0
0
0
0
0
10
0
0
0
0
0
0
10
0
0
% C
% Asp:
0
0
37
0
0
0
0
0
0
10
0
0
10
0
0
% D
% Glu:
0
19
19
10
0
0
0
10
0
55
64
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
10
19
10
19
10
10
10
10
10
10
% G
% His:
0
0
10
0
0
46
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
19
55
0
0
0
0
10
0
0
0
0
10
10
10
0
% K
% Leu:
0
0
0
37
0
0
55
0
10
0
10
0
0
0
0
% L
% Met:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
10
0
19
0
0
0
10
0
0
0
10
10
0
0
% P
% Gln:
0
0
0
0
55
10
0
0
0
0
0
10
0
0
0
% Q
% Arg:
46
10
10
10
19
28
10
19
73
10
0
46
55
64
64
% R
% Ser:
10
10
10
0
10
0
0
55
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _