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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NHLH1 All Species: 35.15
Human Site: T104 Identified Species: 77.33
UniProt: Q02575 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02575 NP_005589.1 133 14618 T104 E L R K L L P T L P P D K K L
Chimpanzee Pan troglodytes Q8MI03 201 20743 P137 A A L P K I I P T L P S D K L
Rhesus Macaque Macaca mulatta XP_001117555 133 14630 T104 E L R K L L P T L P P D K K L
Dog Lupus familis XP_545756 132 14498 T103 E L R K L L P T L P P D K K L
Cat Felis silvestris
Mouse Mus musculus Q02576 133 14811 T104 E L R K L L P T L P P D K K L
Rat Rattus norvegicus Q66HH3 278 29939 T178 E L R K L L P T H P P D R K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514480 139 15024 T110 E L R K L L P T L P P D K K L
Chicken Gallus gallus P24899 311 33749 T208 E L R K L I P T H P P D K K L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_476989 167 18981 T137 E L R K L L P T L P P D K K L
Honey Bee Apis mellifera XP_001122281 93 10416 L65 L R K L L P T L P P D K K L S
Nematode Worm Caenorhab. elegans NP_508440 89 10539 T61 Q L R A L L P T L P V E K K L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 26.3 98.5 94.7 N.A. 92.4 23.3 N.A. 66.1 23.1 N.A. N.A. N.A. 46.1 57.8 45.8 N.A.
Protein Similarity: 100 38.8 99.2 95.4 N.A. 92.4 29.1 N.A. 71.2 29.2 N.A. N.A. N.A. 53.8 61.6 57.1 N.A.
P-Site Identity: 100 20 100 100 N.A. 100 86.6 N.A. 100 86.6 N.A. N.A. N.A. 100 20 73.3 N.A.
P-Site Similarity: 100 26.6 100 100 N.A. 100 93.3 N.A. 100 93.3 N.A. N.A. N.A. 100 26.6 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 10 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 10 73 10 0 0 % D
% Glu: 73 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 19 10 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 10 73 10 0 0 0 0 0 0 10 82 91 0 % K
% Leu: 10 82 10 10 91 73 0 10 64 10 0 0 0 10 91 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 10 0 10 82 10 10 91 82 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 10 82 0 0 0 0 0 0 0 0 0 10 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % S
% Thr: 0 0 0 0 0 0 10 82 10 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _