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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NHLH2
All Species:
41.52
Human Site:
S114
Identified Species:
83.03
UniProt:
Q02577
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02577
NP_001104531.1
135
15018
S114
L
P
P
D
K
K
L
S
K
I
E
I
L
R
L
Chimpanzee
Pan troglodytes
Q8MI03
201
20743
S145
T
L
P
S
D
K
L
S
K
I
Q
T
L
K
L
Rhesus Macaque
Macaca mulatta
XP_001117555
133
14630
S112
L
P
P
D
K
K
L
S
K
I
E
I
L
R
L
Dog
Lupus familis
XP_540253
337
36440
S316
L
P
P
D
K
K
L
S
K
I
E
I
L
R
L
Cat
Felis silvestris
Mouse
Mus musculus
Q64221
135
15014
S114
L
P
P
D
K
K
L
S
K
I
E
I
L
R
L
Rat
Rattus norvegicus
Q66HH3
278
29939
S186
H
P
P
D
R
K
L
S
K
N
E
V
L
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514480
139
15024
S118
L
P
P
D
K
K
L
S
K
I
E
I
L
R
L
Chicken
Gallus gallus
P24899
311
33749
S216
H
P
P
D
K
K
L
S
K
N
E
I
L
R
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
O93507
324
35687
S222
H
P
P
D
K
K
L
S
K
N
E
I
L
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_476989
167
18981
S145
L
P
P
D
K
K
L
S
K
I
E
I
L
K
L
Honey Bee
Apis mellifera
XP_001122281
93
10416
K73
P
P
D
K
K
L
S
K
I
E
I
L
R
L
A
Nematode Worm
Caenorhab. elegans
NP_508440
89
10539
S69
L
P
V
E
K
K
L
S
K
I
E
I
L
R
F
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
21.3
64.4
39.1
N.A.
97
23.7
N.A.
89.2
21.8
N.A.
20
N.A.
47.3
55.5
42.9
N.A.
Protein Similarity:
100
35.3
70.3
39.1
N.A.
97.7
29.1
N.A.
89.9
29.2
N.A.
29.6
N.A.
59.2
60.7
57.7
N.A.
P-Site Identity:
100
53.3
100
100
N.A.
100
73.3
N.A.
100
86.6
N.A.
86.6
N.A.
93.3
13.3
80
N.A.
P-Site Similarity:
100
66.6
100
100
N.A.
100
86.6
N.A.
100
86.6
N.A.
86.6
N.A.
100
20
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
75
9
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
9
84
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
25
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
67
9
75
0
0
0
% I
% Lys:
0
0
0
9
84
92
0
9
92
0
0
0
0
17
0
% K
% Leu:
59
9
0
0
0
9
92
0
0
0
0
9
92
9
84
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% N
% Pro:
9
92
84
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
9
0
0
0
0
0
0
0
9
75
0
% R
% Ser:
0
0
0
9
0
0
9
92
0
0
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% T
% Val:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _