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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TEK All Species: 22.73
Human Site: T996 Identified Species: 41.67
UniProt: Q02763 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02763 NP_000450 1124 125830 T996 Q E V Y V K K T M G R L P V R
Chimpanzee Pan troglodytes XP_520519 1124 125727 T996 Q E V Y V K K T M G R L P V R
Rhesus Macaque Macaca mulatta XP_001105270 1124 125731 T996 Q E V Y V K K T M G R L P V R
Dog Lupus familis XP_539652 1239 135146 T1112 E E V Y V K K T M G R L P V R
Cat Felis silvestris
Mouse Mus musculus Q02858 1122 125682 T994 Q E V Y V K K T M G R L P V R
Rat Rattus norvegicus Q498D6 800 88690 F673 H Q S D V W S F G I L L W E I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505903 1124 124108 V985 D F L R K S R V L E T D P A F
Chicken Gallus gallus P18460 806 89712 W679 W S F G V L L W E I F T L G G
Frog Xenopus laevis O42127 802 89497 W675 W S Y G V L L W E I F T L G G
Zebra Danio Brachydanio rerio O73791 1116 122343 T988 Q E V Y V K K T M G R L P V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07407 729 82568 P602 L P I K W M A P E S L Q E K F
Honey Bee Apis mellifera XP_396649 796 90178 F669 W M A P E A L F H R V Y T T Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26614 972 110463 G845 Q S D V W S F G I L L W E I M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.4 44 N.A. 92.7 25.7 N.A. 69.4 24.2 26.1 52.7 N.A. 23.9 25.2 N.A. 22.6
Protein Similarity: 100 99.1 99.1 57.9 N.A. 96 39.6 N.A. 77.8 40.2 40.7 67.9 N.A. 38.2 41 N.A. 39.5
P-Site Identity: 100 100 100 93.3 N.A. 100 13.3 N.A. 6.6 6.6 6.6 100 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 20 N.A. 26.6 6.6 6.6 100 N.A. 6.6 6.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 8 8 0 0 0 0 0 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 0 8 8 0 0 0 0 0 0 0 8 0 0 0 % D
% Glu: 8 47 0 0 8 0 0 0 24 8 0 0 16 8 0 % E
% Phe: 0 8 8 0 0 0 8 16 0 0 16 0 0 0 16 % F
% Gly: 0 0 0 16 0 0 0 8 8 47 0 0 0 16 16 % G
% His: 8 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 8 24 0 0 0 8 8 % I
% Lys: 0 0 0 8 8 47 47 0 0 0 0 0 0 8 0 % K
% Leu: 8 0 8 0 0 16 24 0 8 8 24 54 16 0 0 % L
% Met: 0 8 0 0 0 8 0 0 47 0 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 8 0 8 0 0 0 8 0 0 0 0 54 0 0 % P
% Gln: 47 8 0 0 0 0 0 0 0 0 0 8 0 0 8 % Q
% Arg: 0 0 0 8 0 0 8 0 0 8 47 0 0 0 47 % R
% Ser: 0 24 8 0 0 16 8 0 0 8 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 47 0 0 8 16 8 8 0 % T
% Val: 0 0 47 8 70 0 0 8 0 0 8 0 0 47 0 % V
% Trp: 24 0 0 0 16 8 0 16 0 0 0 8 8 0 0 % W
% Tyr: 0 0 8 47 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _