Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TEK All Species: 22.42
Human Site: Y1015 Identified Species: 41.11
UniProt: Q02763 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02763 NP_000450 1124 125830 Y1015 E S L N Y S V Y T T N S D V W
Chimpanzee Pan troglodytes XP_520519 1124 125727 Y1015 E S L N Y S V Y T T N S D T V
Rhesus Macaque Macaca mulatta XP_001105270 1124 125731 Y1015 E S L N Y S V Y T T N S D V W
Dog Lupus familis XP_539652 1239 135146 Y1131 E S L N Y S V Y T T K S D V W
Cat Felis silvestris
Mouse Mus musculus Q02858 1122 125682 Y1013 E S L N Y S V Y T T N S D V W
Rat Rattus norvegicus Q498D6 800 88690 P692 G S P Y P G I P V E E L F S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505903 1124 124108 S1004 S T A S T L S S Q Q L L H F A
Chicken Gallus gallus P18460 806 89712 F698 G I P V E E L F K L L K E G H
Frog Xenopus laevis O42127 802 89497 F694 G I P V E E L F K L L K E G H
Zebra Danio Brachydanio rerio O73791 1116 122343 Y1007 E S L N Y S V Y T T N S D V W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07407 729 82568 I621 S D V W S Y G I L L W E I M T
Honey Bee Apis mellifera XP_396649 796 90178 E688 S Y G I L L W E I M T L G G T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26614 972 110463 V864 T P Y P S V P V E Q M F D Y L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.4 44 N.A. 92.7 25.7 N.A. 69.4 24.2 26.1 52.7 N.A. 23.9 25.2 N.A. 22.6
Protein Similarity: 100 99.1 99.1 57.9 N.A. 96 39.6 N.A. 77.8 40.2 40.7 67.9 N.A. 38.2 41 N.A. 39.5
P-Site Identity: 100 86.6 100 93.3 N.A. 100 6.6 N.A. 0 0 0 100 N.A. 0 0 N.A. 6.6
P-Site Similarity: 100 86.6 100 93.3 N.A. 100 13.3 N.A. 13.3 20 20 100 N.A. 13.3 0 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 54 0 0 % D
% Glu: 47 0 0 0 16 16 0 8 8 8 8 8 16 0 0 % E
% Phe: 0 0 0 0 0 0 0 16 0 0 0 8 8 8 0 % F
% Gly: 24 0 8 0 0 8 8 0 0 0 0 0 8 24 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 16 % H
% Ile: 0 16 0 8 0 0 8 8 8 0 0 0 8 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 16 0 8 16 0 0 0 % K
% Leu: 0 0 47 0 8 16 16 0 8 24 24 24 0 0 16 % L
% Met: 0 0 0 0 0 0 0 0 0 8 8 0 0 8 0 % M
% Asn: 0 0 0 47 0 0 0 0 0 0 39 0 0 0 0 % N
% Pro: 0 8 24 8 8 0 8 8 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 8 16 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 24 54 0 8 16 47 8 8 0 0 0 47 0 8 0 % S
% Thr: 8 8 0 0 8 0 0 0 47 47 8 0 0 8 16 % T
% Val: 0 0 8 16 0 8 47 8 8 0 0 0 0 39 8 % V
% Trp: 0 0 0 8 0 0 8 0 0 0 8 0 0 0 39 % W
% Tyr: 0 8 8 8 47 8 0 47 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _