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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TEK All Species: 23.03
Human Site: Y897 Identified Species: 42.22
UniProt: Q02763 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.17
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02763 NP_000450 1124 125830 Y897 G A C E H R G Y L Y L A I E Y
Chimpanzee Pan troglodytes XP_520519 1124 125727 Y897 G A C E H R G Y L Y L A I E Y
Rhesus Macaque Macaca mulatta XP_001105270 1124 125731 Y897 G A C E H R G Y L Y L A I E Y
Dog Lupus familis XP_539652 1239 135146 Y1013 G A C E N R G Y L Y I A I E Y
Cat Felis silvestris
Mouse Mus musculus Q02858 1122 125682 Y895 G A C E H R G Y L Y L A I E Y
Rat Rattus norvegicus Q498D6 800 88690 G580 D G P R S S E G P L S F P A L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505903 1124 124108 F892 L E W N D I K F Q D V I G E G
Chicken Gallus gallus P18460 806 89712 K586 P E E Q L T F K D L V S C A Y
Frog Xenopus laevis O42127 802 89497 K582 P A E Q L T F K D L V S C A Y
Zebra Danio Brachydanio rerio O73791 1116 122343 Y889 G A C E H R G Y L Y L A I E F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07407 729 82568 G509 L Y K N R P F G R D Q D R D S
Honey Bee Apis mellifera XP_396649 796 90178 G576 R D H R P S S G Y E P T I G Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26614 972 110463 T752 I L L T T S Q T L T N K D L M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.4 44 N.A. 92.7 25.7 N.A. 69.4 24.2 26.1 52.7 N.A. 23.9 25.2 N.A. 22.6
Protein Similarity: 100 99.1 99.1 57.9 N.A. 96 39.6 N.A. 77.8 40.2 40.7 67.9 N.A. 38.2 41 N.A. 39.5
P-Site Identity: 100 100 100 86.6 N.A. 100 0 N.A. 6.6 6.6 13.3 93.3 N.A. 0 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 0 N.A. 20 26.6 33.3 100 N.A. 6.6 6.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 54 0 0 0 0 0 0 0 0 0 47 0 24 0 % A
% Cys: 0 0 47 0 0 0 0 0 0 0 0 0 16 0 0 % C
% Asp: 8 8 0 0 8 0 0 0 16 16 0 8 8 8 0 % D
% Glu: 0 16 16 47 0 0 8 0 0 8 0 0 0 54 0 % E
% Phe: 0 0 0 0 0 0 24 8 0 0 0 8 0 0 8 % F
% Gly: 47 8 0 0 0 0 47 24 0 0 0 0 8 8 8 % G
% His: 0 0 8 0 39 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 8 0 0 0 0 8 0 0 0 0 8 8 54 0 0 % I
% Lys: 0 0 8 0 0 0 8 16 0 0 0 8 0 0 0 % K
% Leu: 16 8 8 0 16 0 0 0 54 24 39 0 0 8 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % M
% Asn: 0 0 0 16 8 0 0 0 0 0 8 0 0 0 0 % N
% Pro: 16 0 8 0 8 8 0 0 8 0 8 0 8 0 0 % P
% Gln: 0 0 0 16 0 0 8 0 8 0 8 0 0 0 8 % Q
% Arg: 8 0 0 16 8 47 0 0 8 0 0 0 8 0 0 % R
% Ser: 0 0 0 0 8 24 8 0 0 0 8 16 0 0 8 % S
% Thr: 0 0 0 8 8 16 0 8 0 8 0 8 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 24 0 0 0 0 % V
% Trp: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 47 8 47 0 0 0 0 54 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _