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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TEK All Species: 16.36
Human Site: Y976 Identified Species: 30
UniProt: Q02763 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02763 NP_000450 1124 125830 Y976 N I L V G E N Y V A K I A D F
Chimpanzee Pan troglodytes XP_520519 1124 125727 Y976 N I L V G E N Y V A K I A D F
Rhesus Macaque Macaca mulatta XP_001105270 1124 125731 Y976 N I L V G E N Y V A K I A D F
Dog Lupus familis XP_539652 1239 135146 L1092 N V L V G E N L A S K I A D F
Cat Felis silvestris
Mouse Mus musculus Q02858 1122 125682 Y974 N I L V G E N Y I A K I A D F
Rat Rattus norvegicus Q498D6 800 88690 W653 N G R L P V K W M A P E A L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505903 1124 124108 Y965 C E H R G Y L Y L A I E Y A P
Chicken Gallus gallus P18460 806 89712 A659 V K W M A P E A L F D R V Y T
Frog Xenopus laevis O42127 802 89497 A655 V K W M A P E A L F D R I Y T
Zebra Danio Brachydanio rerio O73791 1116 122343 F968 N V L V G E N F V A K I A D F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q07407 729 82568 Q582 F G L A R D I Q S T D Y Y R K
Honey Bee Apis mellifera XP_396649 796 90178 Y649 R D I H C H D Y Y R K T T D G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26614 972 110463 M825 G R L P V K W M A P E A L F D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 98.4 44 N.A. 92.7 25.7 N.A. 69.4 24.2 26.1 52.7 N.A. 23.9 25.2 N.A. 22.6
Protein Similarity: 100 99.1 99.1 57.9 N.A. 96 39.6 N.A. 77.8 40.2 40.7 67.9 N.A. 38.2 41 N.A. 39.5
P-Site Identity: 100 100 100 73.3 N.A. 93.3 26.6 N.A. 20 0 0 86.6 N.A. 6.6 20 N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 100 46.6 N.A. 26.6 13.3 13.3 100 N.A. 13.3 33.3 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 16 0 0 16 16 54 0 8 54 8 0 % A
% Cys: 8 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 8 8 0 0 0 24 0 0 54 8 % D
% Glu: 0 8 0 0 0 47 16 0 0 0 8 16 0 0 0 % E
% Phe: 8 0 0 0 0 0 0 8 0 16 0 0 0 8 54 % F
% Gly: 8 16 0 0 54 0 0 0 0 0 0 0 0 0 8 % G
% His: 0 0 8 8 0 8 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 31 8 0 0 0 8 0 8 0 8 47 8 0 0 % I
% Lys: 0 16 0 0 0 8 8 0 0 0 54 0 0 0 8 % K
% Leu: 0 0 62 8 0 0 8 8 24 0 0 0 8 8 0 % L
% Met: 0 0 0 16 0 0 0 8 8 0 0 0 0 0 0 % M
% Asn: 54 0 0 0 0 0 47 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 8 8 16 0 0 0 8 8 0 0 0 8 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % Q
% Arg: 8 8 8 8 8 0 0 0 0 8 0 16 0 8 0 % R
% Ser: 0 0 0 0 0 0 0 0 8 8 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 8 0 8 8 0 16 % T
% Val: 16 16 0 47 8 8 0 0 31 0 0 0 8 0 0 % V
% Trp: 0 0 16 0 0 0 8 8 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 47 8 0 0 8 16 16 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _