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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FKBP4 All Species: 23.94
Human Site: S78 Identified Species: 37.62
UniProt: Q02790 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02790 NP_002005.1 459 51805 S78 L D R K D K F S F D L G K G E
Chimpanzee Pan troglodytes XP_508927 414 47057 K76 G S A G S P P K I P P N A T L
Rhesus Macaque Macaca mulatta XP_001098079 459 51670 S78 L D R K D K F S F D L G K G E
Dog Lupus familis XP_534923 459 51500 S78 L D R K D K F S F D L G K G E
Cat Felis silvestris
Mouse Mus musculus P30416 458 51554 S78 L D R K D K F S F D L G K G E
Rat Rattus norvegicus Q9QVC8 458 51432 S78 L D R K D K F S F D L G K G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512517 419 46551 Y78 Q L L C K P E Y A Y G A A G S
Chicken Gallus gallus NP_001006250 442 50413 E78 S F D L G K G E V I K A W D I
Frog Xenopus laevis NP_001084916 447 50310 L77 K D K F T F D L G K G E V I K
Zebra Danio Brachydanio rerio NP_958877 449 50474 G77 E K F S F E L G K G Q V I K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VL78 439 48777 C85 T M K L G E R C F L T C A P N
Honey Bee Apis mellifera XP_395748 459 51510 A84 T M K K G E I A L L T C A P E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781282 422 47590 S77 T D G V L F D S S R S R N E K
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001141458 458 51432 S78 L D R K D K F S F D L G K G E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38931 551 61434 K85 R D R A T P F K F T L G Q G Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.9 98.4 91.7 N.A. 89.7 89.9 N.A. 46.4 74.7 66 61.2 N.A. 41.3 47.7 N.A. 45.9
Protein Similarity: 100 90.1 99.5 97.5 N.A. 95.4 95.2 N.A. 65.3 86 80.6 82.1 N.A. 61 64.4 N.A. 64
P-Site Identity: 100 0 100 100 N.A. 100 100 N.A. 6.6 6.6 6.6 0 N.A. 6.6 13.3 N.A. 13.3
P-Site Similarity: 100 0 100 100 N.A. 100 100 N.A. 6.6 6.6 20 6.6 N.A. 20 33.3 N.A. 20
Percent
Protein Identity: N.A. 89.9 N.A. 28.4 N.A. N.A.
Protein Similarity: N.A. 95.2 N.A. 45 N.A. N.A.
P-Site Identity: N.A. 100 N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. 100 N.A. 60 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 0 7 7 0 0 14 27 0 7 % A
% Cys: 0 0 0 7 0 0 0 7 0 0 0 14 0 0 0 % C
% Asp: 0 60 7 0 40 0 14 0 0 40 0 0 0 7 0 % D
% Glu: 7 0 0 0 0 20 7 7 0 0 0 7 0 7 47 % E
% Phe: 0 7 7 7 7 14 47 0 54 0 0 0 0 0 0 % F
% Gly: 7 0 7 7 20 0 7 7 7 7 14 47 0 54 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 7 0 7 7 0 0 7 7 7 % I
% Lys: 7 7 20 47 7 47 0 14 7 7 7 0 40 7 14 % K
% Leu: 40 7 7 14 7 0 7 7 7 14 47 0 0 0 7 % L
% Met: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 7 % N
% Pro: 0 0 0 0 0 20 7 0 0 7 7 0 0 14 0 % P
% Gln: 7 0 0 0 0 0 0 0 0 0 7 0 7 0 7 % Q
% Arg: 7 0 47 0 0 0 7 0 0 7 0 7 0 0 0 % R
% Ser: 7 7 0 7 7 0 0 47 7 0 7 0 0 0 7 % S
% Thr: 20 0 0 0 14 0 0 0 0 7 14 0 0 7 0 % T
% Val: 0 0 0 7 0 0 0 0 7 0 0 7 7 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _