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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FKBP4
All Species:
21.82
Human Site:
Y302
Identified Species:
34.29
UniProt:
Q02790
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02790
NP_002005.1
459
51805
Y302
K
I
V
S
W
L
E
Y
E
S
S
F
S
N
E
Chimpanzee
Pan troglodytes
XP_508927
414
47057
L285
L
N
L
A
M
C
H
L
K
L
Q
A
F
S
A
Rhesus Macaque
Macaca mulatta
XP_001098079
459
51670
Y302
K
I
V
S
W
L
E
Y
E
S
S
F
S
S
E
Dog
Lupus familis
XP_534923
459
51500
Y302
K
I
I
S
W
L
E
Y
E
S
S
F
S
N
E
Cat
Felis silvestris
Mouse
Mus musculus
P30416
458
51554
Y302
K
I
V
S
W
L
E
Y
E
S
S
F
S
G
E
Rat
Rattus norvegicus
Q9QVC8
458
51432
Y302
K
I
V
S
W
L
E
Y
E
S
S
F
S
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512517
419
46551
L290
L
L
A
A
F
L
N
L
A
M
P
V
L
S
P
Chicken
Gallus gallus
NP_001006250
442
50413
H295
K
I
V
L
W
L
E
H
E
S
G
L
S
D
E
Frog
Xenopus laevis
NP_001084916
447
50310
H298
K
I
M
Q
W
L
E
H
E
S
G
L
S
K
E
Zebra Danio
Brachydanio rerio
NP_958877
449
50474
H297
R
I
V
S
W
L
E
H
E
S
S
M
Q
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VL78
439
48777
A298
E
V
K
K
I
K
V
A
T
H
S
N
I
A
L
Honey Bee
Apis mellifera
XP_395748
459
51510
I298
K
I
E
R
N
N
L
I
L
S
A
H
L
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_781282
422
47590
G291
G
T
N
Y
F
K
Q
G
R
Y
Q
D
A
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141458
458
51432
Y302
K
I
V
S
W
L
E
Y
E
S
S
F
S
G
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38931
551
61434
K309
Q
D
G
T
V
F
L
K
K
G
H
G
E
N
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.9
98.4
91.7
N.A.
89.7
89.9
N.A.
46.4
74.7
66
61.2
N.A.
41.3
47.7
N.A.
45.9
Protein Similarity:
100
90.1
99.5
97.5
N.A.
95.4
95.2
N.A.
65.3
86
80.6
82.1
N.A.
61
64.4
N.A.
64
P-Site Identity:
100
0
93.3
93.3
N.A.
93.3
93.3
N.A.
6.6
66.6
60
60
N.A.
6.6
26.6
N.A.
0
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
93.3
N.A.
33.3
80
73.3
80
N.A.
20
33.3
N.A.
26.6
Percent
Protein Identity:
N.A.
89.9
N.A.
28.4
N.A.
N.A.
Protein Similarity:
N.A.
95.2
N.A.
45
N.A.
N.A.
P-Site Identity:
N.A.
93.3
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
93.3
N.A.
33.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
14
0
0
0
7
7
0
7
7
7
7
7
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
0
0
0
0
0
0
0
0
7
0
7
7
% D
% Glu:
7
0
7
0
0
0
60
0
60
0
0
0
7
0
60
% E
% Phe:
0
0
0
0
14
7
0
0
0
0
0
40
7
0
0
% F
% Gly:
7
0
7
0
0
0
0
7
0
7
14
7
0
20
0
% G
% His:
0
0
0
0
0
0
7
20
0
7
7
7
0
0
0
% H
% Ile:
0
67
7
0
7
0
0
7
0
0
0
0
7
7
0
% I
% Lys:
60
0
7
7
0
14
0
7
14
0
0
0
0
7
7
% K
% Leu:
14
7
7
7
0
67
14
14
7
7
0
14
14
0
14
% L
% Met:
0
0
7
0
7
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
0
7
7
0
7
7
7
0
0
0
0
7
0
27
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
7
0
0
7
7
% P
% Gln:
7
0
0
7
0
0
7
0
0
0
14
0
7
0
0
% Q
% Arg:
7
0
0
7
0
0
0
0
7
0
0
0
0
0
0
% R
% Ser:
0
0
0
47
0
0
0
0
0
67
54
0
54
20
0
% S
% Thr:
0
7
0
7
0
0
0
0
7
0
0
0
0
0
0
% T
% Val:
0
7
47
0
7
0
7
0
0
0
0
7
0
0
0
% V
% Trp:
0
0
0
0
60
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
0
0
0
40
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _