KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GUCY2D
All Species:
11.21
Human Site:
S25
Identified Species:
24.67
UniProt:
Q02846
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02846
NP_000171.1
1103
120059
S25
G
P
A
W
W
A
P
S
L
P
R
L
P
R
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001111670
1103
119842
A25
G
P
A
R
W
A
P
A
L
P
R
L
P
R
A
Dog
Lupus familis
XP_855577
1109
119381
S25
A
P
A
R
W
A
R
S
P
P
R
V
P
G
A
Cat
Felis silvestris
Mouse
Mus musculus
P52785
1108
120707
S25
V
P
A
R
Q
S
P
S
S
F
S
R
V
L
R
Rat
Rattus norvegicus
P51840
1108
120782
S25
I
P
A
W
Q
S
R
S
S
L
S
R
V
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506097
1100
119406
S51
P
A
A
P
W
A
S
S
M
S
L
L
L
W
G
Chicken
Gallus gallus
XP_417281
1078
121075
A22
I
T
I
L
T
S
P
A
H
C
F
V
F
K
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_571939
1107
124988
T39
T
L
P
F
Y
S
I
T
L
W
I
I
L
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q07553
1163
130896
L18
F
S
C
I
L
V
L
L
L
L
G
C
Q
R
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09435
1137
128085
N20
F
P
S
I
F
V
Q
N
L
P
D
T
T
V
A
Sea Urchin
Strong. purpuratus
P16065
1125
126238
T28
A
R
L
D
F
N
P
T
I
I
N
E
D
R
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
97.5
81.8
N.A.
85.1
84.9
N.A.
50.9
53.1
N.A.
50.6
N.A.
28.3
N.A.
26.9
31.3
Protein Similarity:
100
N.A.
98.3
86.9
N.A.
90.1
89.7
N.A.
66.1
69.6
N.A.
68
N.A.
47.1
N.A.
44.4
47.2
P-Site Identity:
100
N.A.
86.6
60
N.A.
26.6
26.6
N.A.
33.3
6.6
N.A.
6.6
N.A.
13.3
N.A.
26.6
13.3
P-Site Similarity:
100
N.A.
93.3
66.6
N.A.
33.3
33.3
N.A.
40
33.3
N.A.
40
N.A.
20
N.A.
46.6
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
10
55
0
0
37
0
19
0
0
0
0
0
0
37
% A
% Cys:
0
0
10
0
0
0
0
0
0
10
0
10
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
10
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% E
% Phe:
19
0
0
10
19
0
0
0
0
10
10
0
10
0
0
% F
% Gly:
19
0
0
0
0
0
0
0
0
0
10
0
0
19
19
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
19
0
10
19
0
0
10
0
10
10
10
10
0
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
10
10
10
10
0
10
10
46
19
10
28
19
19
0
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
10
0
0
10
0
0
0
0
% N
% Pro:
10
55
10
10
0
0
46
0
10
37
0
0
28
0
0
% P
% Gln:
0
0
0
0
19
0
10
0
0
0
0
0
10
0
0
% Q
% Arg:
0
10
0
28
0
0
19
0
0
0
28
19
0
37
19
% R
% Ser:
0
10
10
0
0
37
10
46
19
10
19
0
0
0
10
% S
% Thr:
10
10
0
0
10
0
0
19
0
0
0
10
10
0
0
% T
% Val:
10
0
0
0
0
19
0
0
0
0
0
19
19
10
10
% V
% Trp:
0
0
0
19
37
0
0
0
0
10
0
0
0
10
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _