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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CREB5 All Species: 13.64
Human Site: T478 Identified Species: 42.86
UniProt: Q02930 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02930 NP_001011666.1 508 56858 T478 Q Q V I Q H N T I T T S S S V
Chimpanzee Pan troglodytes XP_519017 571 63858 T541 Q Q V I Q H N T I T T S S S V
Rhesus Macaque Macaca mulatta XP_001088758 422 45564 R393 S N E V T L L R N E V A Q L K
Dog Lupus familis XP_532500 510 57015 T480 Q Q V I Q H N T I T T S S A V
Cat Felis silvestris
Mouse Mus musculus Q8K1L0 357 39937 I328 Q V I Q H N T I T T S S S V S
Rat Rattus norvegicus Q00969 487 52268 V458 T E A G A T S V L T Q M A D Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511527 512 57401 T482 Q Q V I Q H N T I T T S S S V
Chicken Gallus gallus O93602 487 52388 V458 A E A V A T S V L T Q L A D Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.2 34.4 96.8 N.A. 69.6 36 N.A. 93.5 36.8 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.6 47.4 98.2 N.A. 70.2 53.1 N.A. 97 53.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 0 93.3 N.A. 26.6 6.6 N.A. 100 6.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 13.3 100 N.A. 46.6 33.3 N.A. 100 40 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 25 0 25 0 0 0 0 0 0 13 25 13 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 25 0 % D
% Glu: 0 25 13 0 0 0 0 0 0 13 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 13 50 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 13 50 0 0 0 13 50 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 13 % K
% Leu: 0 0 0 0 0 13 13 0 25 0 0 13 0 13 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % M
% Asn: 0 13 0 0 0 13 50 0 13 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 63 50 0 13 50 0 0 0 0 0 25 0 13 0 25 % Q
% Arg: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % R
% Ser: 13 0 0 0 0 0 25 0 0 0 13 63 63 38 13 % S
% Thr: 13 0 0 0 13 25 13 50 13 88 50 0 0 0 0 % T
% Val: 0 13 50 25 0 0 0 25 0 0 13 0 0 13 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _