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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A11
All Species:
23.64
Human Site:
Y259
Identified Species:
47.27
UniProt:
Q02978
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02978
NP_003553.2
314
34062
Y259
M
I
D
G
K
P
E
Y
K
N
G
L
D
V
L
Chimpanzee
Pan troglodytes
XP_001163260
342
37412
Y287
M
I
D
G
K
P
E
Y
K
N
G
L
D
V
L
Rhesus Macaque
Macaca mulatta
XP_001097514
314
34117
Y259
M
I
D
G
K
P
E
Y
K
N
G
L
D
V
L
Dog
Lupus familis
XP_536607
314
34057
Y259
M
I
D
G
K
P
E
Y
K
N
G
L
D
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CR62
314
34136
Y259
M
I
D
G
K
P
E
Y
K
N
G
L
D
V
L
Rat
Rattus norvegicus
P97700
314
34214
Y259
M
I
D
E
K
P
E
Y
K
N
G
L
D
V
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GQ22
291
32540
A237
N
Q
R
S
I
R
D
A
S
N
S
S
Y
K
G
Zebra Danio
Brachydanio rerio
Q9W720
310
33554
N256
G
Q
Y
S
S
A
L
N
C
A
V
A
M
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624399
295
32544
G241
D
G
K
P
E
F
K
G
A
I
D
V
I
I
Q
Nematode Worm
Caenorhab. elegans
NP_493694
306
33289
W252
Y
K
N
A
F
D
V
W
G
K
V
I
K
N
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06143
298
32973
P244
N
G
S
G
D
H
Q
P
A
L
K
I
L
A
D
Red Bread Mold
Neurospora crassa
P0C582
331
35028
T273
K
T
R
L
Q
K
Q
T
R
G
P
D
G
K
L
Conservation
Percent
Protein Identity:
100
91.8
98.7
97.1
N.A.
96.5
96.1
N.A.
N.A.
N.A.
35.9
28
N.A.
N.A.
65.2
68.7
N.A.
Protein Similarity:
100
91.8
100
98
N.A.
97.7
96.8
N.A.
N.A.
N.A.
52.8
46.5
N.A.
N.A.
74.8
76.4
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
N.A.
6.6
0
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
N.A.
N.A.
13.3
6.6
N.A.
N.A.
26.6
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.9
38.3
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
53.1
53.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
6.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
9
0
9
17
9
0
9
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% C
% Asp:
9
0
50
0
9
9
9
0
0
0
9
9
50
0
9
% D
% Glu:
0
0
0
9
9
0
50
0
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
0
50
0
0
0
9
9
9
50
0
9
0
9
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
50
0
0
9
0
0
0
0
9
0
17
9
9
0
% I
% Lys:
9
9
9
0
50
9
9
0
50
9
9
0
9
17
0
% K
% Leu:
0
0
0
9
0
0
9
0
0
9
0
50
9
9
59
% L
% Met:
50
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
17
0
9
0
0
0
0
9
0
59
0
0
0
9
0
% N
% Pro:
0
0
0
9
0
50
0
9
0
0
9
0
0
0
0
% P
% Gln:
0
17
0
0
9
0
17
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
17
0
0
9
0
0
9
0
0
0
0
0
0
% R
% Ser:
0
0
9
17
9
0
0
0
9
0
9
9
0
0
0
% S
% Thr:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
9
% T
% Val:
0
0
0
0
0
0
9
0
0
0
17
9
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
0
0
0
0
50
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _