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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MECOM All Species: 23.03
Human Site: S1023 Identified Species: 50.67
UniProt: Q03112 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03112 NP_001098548.2 1051 118276 S1023 S D K E S L H S T S H S S S N
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093705 1041 117066 S1013 S D K E S L H S T S H S S S N
Dog Lupus familis XP_545272 1312 147394 S1284 S D K E S L H S T S H S S S N
Cat Felis silvestris
Mouse Mus musculus P14404 1042 116829 P1014 S D K D S L H P T S H S S S N
Rat Rattus norvegicus NP_001099893 917 102087 T890 D K D A L H P T S H G S S N V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514858 1260 141585 S1232 S D K D S L H S T S H N S P N
Chicken Gallus gallus XP_422804 1115 125799 S1087 S D K D S L H S A S H N S P N
Frog Xenopus laevis B7ZRU9 1055 118966 P1027 S D Q E S L H P T T H T S S S
Zebra Danio Brachydanio rerio XP_001922927 1153 129171 S1125 S E N T N L H S S S Q N S L D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121599 1541 171480 R1497 Q L Q L E E K R G D S S Y F S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798234 1723 193143 S1678 E S G D L D R S R L N G R H P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.5 77.1 N.A. 92.4 79.5 N.A. 77.1 64.6 78.1 50.9 N.A. N.A. 20.1 N.A. 22.4
Protein Similarity: 100 N.A. 98.7 78 N.A. 95.2 82.2 N.A. 79.7 74 87.4 64.5 N.A. N.A. 34.5 N.A. 35.4
P-Site Identity: 100 N.A. 100 100 N.A. 86.6 13.3 N.A. 80 73.3 66.6 40 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 100 100 N.A. 93.3 33.3 N.A. 93.3 86.6 93.3 73.3 N.A. N.A. 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 10 0 0 0 0 10 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 64 10 37 0 10 0 0 0 10 0 0 0 0 10 % D
% Glu: 10 10 0 37 10 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 10 0 0 0 0 0 10 0 10 10 0 0 0 % G
% His: 0 0 0 0 0 10 73 0 0 10 64 0 0 10 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 55 0 0 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 10 19 73 0 0 0 10 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 10 0 10 0 0 0 0 0 10 28 0 10 55 % N
% Pro: 0 0 0 0 0 0 10 19 0 0 0 0 0 19 10 % P
% Gln: 10 0 19 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 10 10 0 0 0 10 0 0 % R
% Ser: 73 10 0 0 64 0 0 64 19 64 10 55 82 46 19 % S
% Thr: 0 0 0 10 0 0 0 10 55 10 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _