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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MECOM
All Species:
17.27
Human Site:
S45
Identified Species:
38
UniProt:
Q03112
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03112
NP_001098548.2
1051
118276
S45
D
H
Q
K
F
P
C
S
T
P
H
S
A
F
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093705
1041
117066
E45
H
S
A
F
S
M
V
E
E
D
F
Q
Q
K
L
Dog
Lupus familis
XP_545272
1312
147394
S301
D
H
Q
K
F
P
C
S
T
P
H
S
A
F
S
Cat
Felis silvestris
Mouse
Mus musculus
P14404
1042
116829
S45
D
H
Q
K
F
P
C
S
T
P
H
S
A
F
S
Rat
Rattus norvegicus
NP_001099893
917
102087
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514858
1260
141585
S263
D
H
Q
K
F
P
C
S
T
P
H
S
A
F
S
Chicken
Gallus gallus
XP_422804
1115
125799
T54
I
Q
E
P
S
S
P
T
T
S
S
E
A
F
T
Frog
Xenopus laevis
B7ZRU9
1055
118966
V45
D
H
Q
K
Y
P
C
V
T
P
H
S
A
F
S
Zebra Danio
Brachydanio rerio
XP_001922927
1153
129171
D88
M
Y
R
C
E
H
C
D
E
L
F
T
S
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121599
1541
171480
S117
R
D
E
E
K
P
S
S
W
E
Y
G
E
K
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798234
1723
193143
G440
S
E
S
M
K
D
I
G
C
I
A
F
Q
G
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
77.1
N.A.
92.4
79.5
N.A.
77.1
64.6
78.1
50.9
N.A.
N.A.
20.1
N.A.
22.4
Protein Similarity:
100
N.A.
98.7
78
N.A.
95.2
82.2
N.A.
79.7
74
87.4
64.5
N.A.
N.A.
34.5
N.A.
35.4
P-Site Identity:
100
N.A.
0
100
N.A.
100
0
N.A.
100
20
86.6
6.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
N.A.
0
100
N.A.
100
0
N.A.
100
40
93.3
33.3
N.A.
N.A.
40
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
10
0
55
0
0
% A
% Cys:
0
0
0
10
0
0
55
0
10
0
0
0
0
0
0
% C
% Asp:
46
10
0
0
0
10
0
10
0
10
0
0
0
0
0
% D
% Glu:
0
10
19
10
10
0
0
10
19
10
0
10
10
0
0
% E
% Phe:
0
0
0
10
37
0
0
0
0
0
19
10
0
55
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
0
0
10
0
10
0
% G
% His:
10
46
0
0
0
10
0
0
0
0
46
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
46
19
0
0
0
0
0
0
0
0
28
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
28
% L
% Met:
10
0
0
10
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
55
10
0
0
46
0
0
0
0
0
% P
% Gln:
0
10
46
0
0
0
0
0
0
0
0
10
19
0
0
% Q
% Arg:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
10
10
0
19
10
10
46
0
10
10
46
10
0
46
% S
% Thr:
0
0
0
0
0
0
0
10
55
0
0
10
0
0
19
% T
% Val:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
10
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _