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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MECOM
All Species:
22.73
Human Site:
S593
Identified Species:
50
UniProt:
Q03112
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03112
NP_001098548.2
1051
118276
S593
D
L
S
M
G
S
R
S
R
A
S
G
T
K
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093705
1041
117066
S583
D
L
S
M
G
S
R
S
R
A
S
G
T
K
L
Dog
Lupus familis
XP_545272
1312
147394
S849
D
L
S
M
G
S
R
S
R
A
S
G
T
K
L
Cat
Felis silvestris
Mouse
Mus musculus
P14404
1042
116829
G593
D
L
S
M
G
S
R
G
R
A
S
G
T
K
L
Rat
Rattus norvegicus
NP_001099893
917
102087
G492
E
T
R
P
S
S
D
G
S
L
Q
H
A
R
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514858
1260
141585
S811
D
L
S
M
G
S
R
S
R
A
S
G
T
K
Q
Chicken
Gallus gallus
XP_422804
1115
125799
S665
D
L
S
M
G
S
R
S
R
A
S
S
T
K
Q
Frog
Xenopus laevis
B7ZRU9
1055
118966
S594
D
L
S
M
G
S
R
S
R
A
A
T
T
K
Q
Zebra Danio
Brachydanio rerio
XP_001922927
1153
129171
D666
S
G
E
E
Q
P
L
D
L
S
I
G
S
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121599
1541
171480
H1052
A
G
T
A
Q
Q
Q
H
G
R
T
R
D
R
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798234
1723
193143
T1111
E
E
W
L
Q
H
Y
T
V
G
A
G
R
D
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
77.1
N.A.
92.4
79.5
N.A.
77.1
64.6
78.1
50.9
N.A.
N.A.
20.1
N.A.
22.4
Protein Similarity:
100
N.A.
98.7
78
N.A.
95.2
82.2
N.A.
79.7
74
87.4
64.5
N.A.
N.A.
34.5
N.A.
35.4
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
6.6
N.A.
93.3
86.6
80
6.6
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
20
N.A.
93.3
86.6
86.6
26.6
N.A.
N.A.
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
0
64
19
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
64
0
0
0
0
0
10
10
0
0
0
0
10
10
10
% D
% Glu:
19
10
10
10
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
19
0
0
64
0
0
19
10
10
0
64
0
0
0
% G
% His:
0
0
0
0
0
10
0
10
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
64
0
% K
% Leu:
0
64
0
10
0
0
10
0
10
10
0
0
0
0
37
% L
% Met:
0
0
0
64
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
28
10
10
0
0
0
10
0
0
0
37
% Q
% Arg:
0
0
10
0
0
0
64
0
64
10
0
10
10
28
0
% R
% Ser:
10
0
64
0
10
73
0
55
10
10
55
10
10
0
10
% S
% Thr:
0
10
10
0
0
0
0
10
0
0
10
10
64
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _