Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MECOM All Species: 28.18
Human Site: S663 Identified Species: 62
UniProt: Q03112 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03112 NP_001098548.2 1051 118276 S663 K E K Y L R P S P G F L F H P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093705 1041 117066 S653 K E K Y L R P S P G F L F H P
Dog Lupus familis XP_545272 1312 147394 S919 K E K Y L R P S P G F L F H P
Cat Felis silvestris
Mouse Mus musculus P14404 1042 116829 S663 K E K Y L R P S P G F L F H P
Rat Rattus norvegicus NP_001099893 917 102087 S562 A E K L E S F S G L K P E A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514858 1260 141585 S881 K E K Y L R P S P G F L F H P
Chicken Gallus gallus XP_422804 1115 125799 S735 K E K Y L R P S P G F L F H P
Frog Xenopus laevis B7ZRU9 1055 118966 S664 K E K Y L R P S P G F L F H P
Zebra Danio Brachydanio rerio XP_001922927 1153 129171 K736 Q P S L H Y A K P S P F F M D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121599 1541 171480 K1122 M P G H I S P K Q A S I Y P L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798234 1723 193143 D1181 F V K K E N P D E G G I K E C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.5 77.1 N.A. 92.4 79.5 N.A. 77.1 64.6 78.1 50.9 N.A. N.A. 20.1 N.A. 22.4
Protein Similarity: 100 N.A. 98.7 78 N.A. 95.2 82.2 N.A. 79.7 74 87.4 64.5 N.A. N.A. 34.5 N.A. 35.4
P-Site Identity: 100 N.A. 100 100 N.A. 100 20 N.A. 100 100 100 13.3 N.A. N.A. 6.6 N.A. 20
P-Site Similarity: 100 N.A. 100 100 N.A. 100 20 N.A. 100 100 100 20 N.A. N.A. 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 10 0 0 10 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % D
% Glu: 0 73 0 0 19 0 0 0 10 0 0 0 10 10 0 % E
% Phe: 10 0 0 0 0 0 10 0 0 0 64 10 73 0 0 % F
% Gly: 0 0 10 0 0 0 0 0 10 73 10 0 0 0 0 % G
% His: 0 0 0 10 10 0 0 0 0 0 0 0 0 64 0 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 19 0 0 0 % I
% Lys: 64 0 82 10 0 0 0 19 0 0 10 0 10 0 0 % K
% Leu: 0 0 0 19 64 0 0 0 0 10 0 64 0 0 10 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 19 0 0 0 0 82 0 73 0 10 10 0 10 64 % P
% Gln: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 64 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 10 0 0 19 0 73 0 10 10 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 64 0 10 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _