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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MECOM All Species: 34.85
Human Site: S773 Identified Species: 76.67
UniProt: Q03112 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03112 NP_001098548.2 1051 118276 S773 C D R S F S I S S N L Q R H V
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001093705 1041 117066 S763 C D R S F S I S S N L Q R H V
Dog Lupus familis XP_545272 1312 147394 S1020 C D R S F S I S S N L Q R H V
Cat Felis silvestris
Mouse Mus musculus P14404 1042 116829 S764 C D R S F S I S S N L Q R H V
Rat Rattus norvegicus NP_001099893 917 102087 D663 P F K C H L C D R C F G Q Q T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514858 1260 141585 S982 C D R S F S I S S N L Q R H V
Chicken Gallus gallus XP_422804 1115 125799 S836 C D R S F S I S S N L Q R H V
Frog Xenopus laevis B7ZRU9 1055 118966 S774 C D R S F S I S S N L Q R H V
Zebra Danio Brachydanio rerio XP_001922927 1153 129171 S869 C D R S F S I S S N L Q R H V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121599 1541 171480 E1240 T V H P L V L E A M Y R S H H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798234 1723 193143 S1442 C G K L F P R S A N L T R H L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.5 77.1 N.A. 92.4 79.5 N.A. 77.1 64.6 78.1 50.9 N.A. N.A. 20.1 N.A. 22.4
Protein Similarity: 100 N.A. 98.7 78 N.A. 95.2 82.2 N.A. 79.7 74 87.4 64.5 N.A. N.A. 34.5 N.A. 35.4
P-Site Identity: 100 N.A. 100 100 N.A. 100 0 N.A. 100 100 100 100 N.A. N.A. 6.6 N.A. 46.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 13.3 N.A. 100 100 100 100 N.A. N.A. 26.6 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 19 0 0 0 0 0 0 % A
% Cys: 82 0 0 10 0 0 10 0 0 10 0 0 0 0 0 % C
% Asp: 0 73 0 0 0 0 0 10 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 82 0 0 0 0 0 10 0 0 0 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 0 10 0 10 0 0 0 0 0 0 0 0 91 10 % H
% Ile: 0 0 0 0 0 0 73 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 19 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 10 10 10 10 0 0 0 82 0 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 82 0 0 0 0 0 % N
% Pro: 10 0 0 10 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 73 10 10 0 % Q
% Arg: 0 0 73 0 0 0 10 0 10 0 0 10 82 0 0 % R
% Ser: 0 0 0 73 0 73 0 82 73 0 0 0 10 0 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % T
% Val: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 73 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _