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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MECOM
All Species:
30
Human Site:
S990
Identified Species:
66
UniProt:
Q03112
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03112
NP_001098548.2
1051
118276
S990
E
L
S
S
F
S
T
S
H
V
P
E
E
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093705
1041
117066
S980
E
L
S
S
F
S
T
S
H
V
P
E
E
L
K
Dog
Lupus familis
XP_545272
1312
147394
S1251
E
L
S
S
F
S
A
S
H
V
P
E
E
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P14404
1042
116829
S981
E
L
S
S
I
S
S
S
H
V
P
E
E
L
K
Rat
Rattus norvegicus
NP_001099893
917
102087
H857
E
L
S
F
G
S
S
H
V
P
E
E
L
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514858
1260
141585
S1199
E
L
A
S
F
S
T
S
H
L
P
E
D
L
K
Chicken
Gallus gallus
XP_422804
1115
125799
S1054
E
L
A
A
F
N
T
S
Q
L
P
E
D
L
K
Frog
Xenopus laevis
B7ZRU9
1055
118966
S994
E
L
S
A
F
T
A
S
H
L
T
D
D
L
K
Zebra Danio
Brachydanio rerio
XP_001922927
1153
129171
S1092
I
K
D
I
F
S
P
S
V
E
S
E
A
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121599
1541
171480
T1464
R
S
F
M
G
K
I
T
S
Q
R
Q
G
I
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798234
1723
193143
S1645
S
D
D
A
M
S
V
S
E
Y
Q
D
D
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
77.1
N.A.
92.4
79.5
N.A.
77.1
64.6
78.1
50.9
N.A.
N.A.
20.1
N.A.
22.4
Protein Similarity:
100
N.A.
98.7
78
N.A.
95.2
82.2
N.A.
79.7
74
87.4
64.5
N.A.
N.A.
34.5
N.A.
35.4
P-Site Identity:
100
N.A.
100
93.3
N.A.
86.6
33.3
N.A.
80
60
53.3
40
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
46.6
N.A.
100
93.3
86.6
40
N.A.
N.A.
20
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
19
28
0
0
19
0
0
0
0
0
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
19
0
0
0
0
0
0
0
0
19
37
10
10
% D
% Glu:
73
0
0
0
0
0
0
0
10
10
10
73
37
0
0
% E
% Phe:
0
0
10
10
64
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
19
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
10
55
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
10
0
10
0
0
0
0
0
0
10
0
% I
% Lys:
0
10
0
0
0
10
0
0
0
0
0
0
0
10
73
% K
% Leu:
0
73
0
0
0
0
0
0
0
28
0
0
10
73
0
% L
% Met:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
10
0
0
10
55
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
10
10
10
0
0
10
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% R
% Ser:
10
10
55
46
0
73
19
82
10
0
10
0
0
0
0
% S
% Thr:
0
0
0
0
0
10
37
10
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
10
0
19
37
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _