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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MECOM
All Species:
22.73
Human Site:
T649
Identified Species:
50
UniProt:
Q03112
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03112
NP_001098548.2
1051
118276
T649
R
V
E
K
R
K
L
T
D
P
L
E
A
L
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093705
1041
117066
T639
R
V
E
K
R
K
L
T
D
P
L
E
A
L
K
Dog
Lupus familis
XP_545272
1312
147394
T905
R
V
E
K
R
K
L
T
D
P
L
E
A
L
K
Cat
Felis silvestris
Mouse
Mus musculus
P14404
1042
116829
T649
R
V
E
K
R
K
L
T
D
P
L
E
A
L
K
Rat
Rattus norvegicus
NP_001099893
917
102087
M548
L
P
D
Q
R
T
W
M
S
A
I
E
N
M
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514858
1260
141585
T867
R
V
E
K
R
K
L
T
D
P
L
E
A
L
K
Chicken
Gallus gallus
XP_422804
1115
125799
T721
R
V
E
K
R
K
L
T
D
P
L
E
A
L
K
Frog
Xenopus laevis
B7ZRU9
1055
118966
M650
R
V
E
K
R
K
P
M
D
P
L
E
I
L
K
Zebra Danio
Brachydanio rerio
XP_001922927
1153
129171
Q722
Q
Q
H
T
S
L
P
Q
P
P
V
P
Q
Q
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121599
1541
171480
K1108
Y
P
P
A
M
R
E
K
D
S
S
P
R
K
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798234
1723
193143
K1167
E
A
D
M
E
I
T
K
A
K
R
V
A
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
77.1
N.A.
92.4
79.5
N.A.
77.1
64.6
78.1
50.9
N.A.
N.A.
20.1
N.A.
22.4
Protein Similarity:
100
N.A.
98.7
78
N.A.
95.2
82.2
N.A.
79.7
74
87.4
64.5
N.A.
N.A.
34.5
N.A.
35.4
P-Site Identity:
100
N.A.
100
100
N.A.
100
13.3
N.A.
100
100
80
6.6
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
40
N.A.
100
100
80
26.6
N.A.
N.A.
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
0
0
0
0
10
10
0
0
64
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
0
0
0
73
0
0
0
0
0
0
% D
% Glu:
10
0
64
0
10
0
10
0
0
0
0
73
0
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
10
0
0
0
0
10
0
10
0
0
% I
% Lys:
0
0
0
64
0
64
0
19
0
10
0
0
0
10
64
% K
% Leu:
10
0
0
0
0
10
55
0
0
0
64
0
0
64
0
% L
% Met:
0
0
0
10
10
0
0
19
0
0
0
0
0
10
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
19
10
0
0
0
19
0
10
73
0
19
0
0
0
% P
% Gln:
10
10
0
10
0
0
0
10
0
0
0
0
10
10
10
% Q
% Arg:
64
0
0
0
73
10
0
0
0
0
10
0
10
0
0
% R
% Ser:
0
0
0
0
10
0
0
0
10
10
10
0
0
0
0
% S
% Thr:
0
0
0
10
0
10
10
55
0
0
0
0
0
0
0
% T
% Val:
0
64
0
0
0
0
0
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _