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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MECOM
All Species:
15.76
Human Site:
Y21
Identified Species:
34.67
UniProt:
Q03112
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03112
NP_001098548.2
1051
118276
Y21
D
I
H
E
E
R
Q
Y
R
C
E
D
C
D
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093705
1041
117066
E21
E
D
C
D
Q
L
F
E
S
K
A
D
L
A
D
Dog
Lupus familis
XP_545272
1312
147394
Y277
D
I
H
E
E
R
Q
Y
R
C
E
D
C
D
Q
Cat
Felis silvestris
Mouse
Mus musculus
P14404
1042
116829
H21
D
I
H
E
E
R
Q
H
R
C
E
D
C
D
Q
Rat
Rattus norvegicus
NP_001099893
917
102087
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514858
1260
141585
Y239
D
I
H
E
E
R
Q
Y
R
C
E
D
C
D
Q
Chicken
Gallus gallus
XP_422804
1115
125799
P30
E
L
P
L
E
D
V
P
E
A
D
G
E
A
A
Frog
Xenopus laevis
B7ZRU9
1055
118966
Y21
D
I
H
E
E
R
Q
Y
R
C
E
E
C
D
Q
Zebra Danio
Brachydanio rerio
XP_001922927
1153
129171
D64
E
L
L
V
Y
M
K
D
G
V
F
P
E
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121599
1541
171480
A93
Y
Q
R
G
Y
S
P
A
M
D
K
P
S
Y
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798234
1723
193143
S416
S
L
Q
E
Q
Y
F
S
K
P
N
E
L
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
98.5
77.1
N.A.
92.4
79.5
N.A.
77.1
64.6
78.1
50.9
N.A.
N.A.
20.1
N.A.
22.4
Protein Similarity:
100
N.A.
98.7
78
N.A.
95.2
82.2
N.A.
79.7
74
87.4
64.5
N.A.
N.A.
34.5
N.A.
35.4
P-Site Identity:
100
N.A.
6.6
100
N.A.
93.3
0
N.A.
100
6.6
93.3
0
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
N.A.
26.6
100
N.A.
100
0
N.A.
100
26.6
100
20
N.A.
N.A.
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
10
10
0
0
19
10
% A
% Cys:
0
0
10
0
0
0
0
0
0
46
0
0
46
0
0
% C
% Asp:
46
10
0
10
0
10
0
10
0
10
10
46
0
46
10
% D
% Glu:
28
0
0
55
55
0
0
10
10
0
46
19
19
10
19
% E
% Phe:
0
0
0
0
0
0
19
0
0
0
10
0
0
0
0
% F
% Gly:
0
0
0
10
0
0
0
0
10
0
0
10
0
10
0
% G
% His:
0
0
46
0
0
0
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
46
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
10
0
10
10
10
0
0
0
0
% K
% Leu:
0
28
10
10
0
10
0
0
0
0
0
0
19
0
0
% L
% Met:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
10
0
0
0
10
10
0
10
0
19
0
0
0
% P
% Gln:
0
10
10
0
19
0
46
0
0
0
0
0
0
0
46
% Q
% Arg:
0
0
10
0
0
46
0
0
46
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
10
0
10
10
0
0
0
10
0
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
19
10
0
37
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _