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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNA12 All Species: 17.27
Human Site: S155 Identified Species: 27.14
UniProt: Q03113 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03113 NP_031379.2 381 44279 S155 Q L Y V P A L S A L W R D S G
Chimpanzee Pan troglodytes XP_001137775 309 35950 S106 S E F Q L G E S V K Y F L D N
Rhesus Macaque Macaca mulatta XP_001087455 283 33176 S80 S E F Q L G E S V K Y F L D N
Dog Lupus familis XP_851937 282 33193 S79 S E F Q L G E S V K Y F L D N
Cat Felis silvestris
Mouse Mus musculus P27600 379 44077 S153 Q L Y V P A L S A L W R D S G
Rat Rattus norvegicus Q63210 379 44047 S153 Q L Y V P A L S A L W R D S G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513257 282 33131 S79 S E Y Q L G E S V K Y F L D N
Chicken Gallus gallus XP_001233237 388 45295 C162 Q L Y V P A L C A L W R D S G
Frog Xenopus laevis P38410 359 42198 K133 N P Y V D A I K Y L W N D P G
Zebra Danio Brachydanio rerio NP_001013295 385 44942 Q159 Q L Y V P A L Q A L W N D S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25157 457 52735 S227 M E Y A P P I S R L W Q D R G
Honey Bee Apis mellifera XP_394382 369 43544 Q141 L H Y V P A L Q S L W K D A S
Nematode Worm Caenorhab. elegans Q19572 355 41956 S129 V E V A P I I S D F W N D A A
Sea Urchin Strong. purpuratus NP_001001476 362 42149 V135 V Q Y V Q P C V E L W K D S G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q05425 353 40868 E128 P E V G N A I E A L W R D A G
Conservation
Percent
Protein Identity: 100 76.9 74.2 72.6 N.A. 98.1 97.9 N.A. 71.3 88.1 43.5 85.4 N.A. 45.9 56.4 48.5 58.5
Protein Similarity: 100 78.2 74.2 73.7 N.A. 99.2 98.9 N.A. 73.4 92.5 60.6 91.6 N.A. 59 74 67.4 74.5
P-Site Identity: 100 6.6 6.6 6.6 N.A. 100 100 N.A. 13.3 93.3 46.6 86.6 N.A. 46.6 53.3 26.6 46.6
P-Site Similarity: 100 20 20 20 N.A. 100 100 N.A. 20 93.3 53.3 86.6 N.A. 60 73.3 40 53.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 38
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 58
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 46.6
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 60
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 14 0 54 0 0 40 0 0 0 0 20 7 % A
% Cys: 0 0 0 0 0 0 7 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 7 0 0 0 7 0 0 0 74 27 0 % D
% Glu: 0 47 0 0 0 0 27 7 7 0 0 0 0 0 0 % E
% Phe: 0 0 20 0 0 0 0 0 0 7 0 27 0 0 0 % F
% Gly: 0 0 0 7 0 27 0 0 0 0 0 0 0 0 60 % G
% His: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 7 27 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 7 0 27 0 14 0 0 0 % K
% Leu: 7 34 0 0 27 0 40 0 0 67 0 0 27 0 0 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 7 0 0 0 0 0 0 20 0 0 27 % N
% Pro: 7 7 0 0 54 14 0 0 0 0 0 0 0 7 0 % P
% Gln: 34 7 0 27 7 0 0 14 0 0 0 7 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 7 0 0 34 0 7 0 % R
% Ser: 27 0 0 0 0 0 0 60 7 0 0 0 0 40 7 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 14 0 14 54 0 0 0 7 27 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 74 0 0 0 0 % W
% Tyr: 0 0 67 0 0 0 0 0 7 0 27 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _