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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: GNA12 All Species: 35.76
Human Site: T208 Identified Species: 56.19
UniProt: Q03113 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03113 NP_031379.2 381 44279 T208 I L L A R K A T K G I V E H D
Chimpanzee Pan troglodytes XP_001137775 309 35950 Q159 K M V D V G G Q R S Q R Q K W
Rhesus Macaque Macaca mulatta XP_001087455 283 33176 Q133 K M V D V G G Q R S Q R Q K W
Dog Lupus familis XP_851937 282 33193 Q132 K M V D V G G Q R S Q R Q K W
Cat Felis silvestris
Mouse Mus musculus P27600 379 44077 T206 I L L A R K A T K G I V E H D
Rat Rattus norvegicus Q63210 379 44047 T206 I L L A R K A T K G I V E H D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513257 282 33131 Q132 K M V D V G G Q R S Q R Q K W
Chicken Gallus gallus XP_001233237 388 45295 T215 I L L A R K A T K G I V E H D
Frog Xenopus laevis P38410 359 42198 T186 V L R V R V P T T G I I E Y P
Zebra Danio Brachydanio rerio NP_001013295 385 44942 T212 I L L A R K A T K G I V E H D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25157 457 52735 T280 I L H C R K A T K G V Y E F C
Honey Bee Apis mellifera XP_394382 369 43544 T194 I L H C R K A T K G I S E F V
Nematode Worm Caenorhab. elegans Q19572 355 41956 T182 I L F C R K A T R G I S E H I
Sea Urchin Strong. purpuratus NP_001001476 362 42149 T188 I L H S R K A T K A F Q E H V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q05425 353 40868 T181 V L R S R V K T T G I T E T T
Conservation
Percent
Protein Identity: 100 76.9 74.2 72.6 N.A. 98.1 97.9 N.A. 71.3 88.1 43.5 85.4 N.A. 45.9 56.4 48.5 58.5
Protein Similarity: 100 78.2 74.2 73.7 N.A. 99.2 98.9 N.A. 73.4 92.5 60.6 91.6 N.A. 59 74 67.4 74.5
P-Site Identity: 100 0 0 0 N.A. 100 100 N.A. 0 100 40 100 N.A. 60 66.6 66.6 60
P-Site Similarity: 100 26.6 26.6 26.6 N.A. 100 100 N.A. 26.6 100 60 100 N.A. 66.6 66.6 73.3 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 38
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 58
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 40
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 53.3
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 34 0 0 60 0 0 7 0 0 0 0 0 % A
% Cys: 0 0 0 20 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 0 0 27 0 0 0 0 0 0 0 0 0 0 34 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 74 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 0 0 7 0 0 14 0 % F
% Gly: 0 0 0 0 0 27 27 0 0 67 0 0 0 0 0 % G
% His: 0 0 20 0 0 0 0 0 0 0 0 0 0 47 0 % H
% Ile: 60 0 0 0 0 0 0 0 0 0 60 7 0 0 7 % I
% Lys: 27 0 0 0 0 60 7 0 54 0 0 0 0 27 0 % K
% Leu: 0 74 34 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 27 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % P
% Gln: 0 0 0 0 0 0 0 27 0 0 27 7 27 0 0 % Q
% Arg: 0 0 14 0 74 0 0 0 34 0 0 27 0 0 0 % R
% Ser: 0 0 0 14 0 0 0 0 0 27 0 14 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 74 14 0 0 7 0 7 7 % T
% Val: 14 0 27 7 27 14 0 0 0 0 7 34 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 27 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _