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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACY1
All Species:
42.73
Human Site:
T214
Identified Species:
85.45
UniProt:
Q03154
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03154
NP_000657.1
408
45885
T214
A
S
R
F
M
E
D
T
A
A
E
K
L
H
K
Chimpanzee
Pan troglodytes
XP_001170530
437
48871
T243
A
S
R
F
M
E
D
T
A
A
E
K
L
H
K
Rhesus Macaque
Macaca mulatta
XP_001091857
512
56303
T318
G
S
L
F
I
E
D
T
A
A
E
K
L
H
K
Dog
Lupus familis
XP_533806
408
45369
T214
G
S
R
F
I
E
D
T
A
A
E
K
L
H
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99JW2
408
45762
T214
A
S
R
F
I
E
D
T
A
A
E
K
L
H
K
Rat
Rattus norvegicus
Q6PTT0
408
45804
T214
A
S
R
F
M
E
D
T
A
A
E
K
L
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506809
480
53529
T286
G
S
R
F
I
E
D
T
A
G
E
K
L
N
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001086906
407
46015
T213
G
S
R
F
I
E
N
T
A
A
A
K
L
H
S
Zebra Danio
Brachydanio rerio
NP_957289
420
47351
T226
G
S
R
F
V
E
N
T
A
A
E
K
L
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650004
401
45112
T214
G
S
L
L
L
P
N
T
A
G
E
K
L
N
Y
Honey Bee
Apis mellifera
XP_392498
401
45286
T215
G
S
L
L
L
D
N
T
A
G
E
K
I
R
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783286
472
52934
T219
A
S
K
F
V
E
D
T
A
A
E
K
A
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.3
60.3
87.7
N.A.
85.7
93.1
N.A.
63.3
N.A.
59.3
59
N.A.
47.5
48.7
N.A.
46.1
Protein Similarity:
100
93.3
66.8
93.1
N.A.
92.4
96.5
N.A.
72.9
N.A.
75.4
75.7
N.A.
62.7
68.3
N.A.
61.2
P-Site Identity:
100
100
80
86.6
N.A.
93.3
100
N.A.
73.3
N.A.
66.6
66.6
N.A.
40
33.3
N.A.
66.6
P-Site Similarity:
100
100
86.6
93.3
N.A.
100
100
N.A.
86.6
N.A.
80
86.6
N.A.
60
60
N.A.
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
42
0
0
0
0
0
0
0
100
75
9
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
9
67
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
84
0
0
0
0
92
0
0
0
0
% E
% Phe:
0
0
0
84
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
59
0
0
0
0
0
0
0
0
25
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
59
0
% H
% Ile:
0
0
0
0
42
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
0
0
9
0
0
0
0
0
0
0
0
100
0
0
59
% K
% Leu:
0
0
25
17
17
0
0
0
0
0
0
0
84
0
0
% L
% Met:
0
0
0
0
25
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
34
0
0
0
0
0
0
17
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
67
0
0
0
0
0
0
0
0
0
0
25
17
% R
% Ser:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _