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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MLL All Species: 15.15
Human Site: T3213 Identified Species: 33.33
UniProt: Q03164 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03164 NP_005924.2 3969 431764 T3213 D L S T T V A T P S S G L K K
Chimpanzee Pan troglodytes XP_508792 3969 431708 T3213 D L S T T V A T P S S G L K K
Rhesus Macaque Macaca mulatta XP_001093874 3983 436106 T3227 D L S T T V A T P S S G L K K
Dog Lupus familis XP_536554 3923 428640 T3172 D L S T T V A T P S S G L K K
Cat Felis silvestris
Mouse Mus musculus P55200 3966 429631 P3210 L T T T V A T P S S G L K K R
Rat Rattus norvegicus NP_001101609 3725 405813 A2990 T R K N K K L A P S S A P S N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417896 1716 188201 S1005 G R G G L D K S D L D L S P A
Frog Xenopus laevis Q66J90 1938 216239 V1227 P D N A P P A V Q E P M I I R
Zebra Danio Brachydanio rerio NP_001103749 4218 456340 M3465 D H A P N V A M V S S A S T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20659 3726 400080 T3001 Q P S M P I I T L A E A P V V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001190252 5353 591425 D4522 K K V I I G K D V T T N Q V I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 95.8 92.4 N.A. 91.1 85 N.A. N.A. 33.3 20 46.4 N.A. 20.6 N.A. N.A. 22.6
Protein Similarity: 100 99.8 96.5 94.3 N.A. 94.2 87.8 N.A. N.A. 36.5 30.6 59.7 N.A. 36.3 N.A. N.A. 37.6
P-Site Identity: 100 100 100 100 N.A. 20 20 N.A. N.A. 0 6.6 33.3 N.A. 13.3 N.A. N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 33.3 20 N.A. N.A. 6.6 26.6 40 N.A. 26.6 N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 10 0 10 55 10 0 10 0 28 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 46 10 0 0 0 10 0 10 10 0 10 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 10 10 0 10 0 0 0 0 10 37 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 10 10 10 0 0 0 0 0 10 10 19 % I
% Lys: 10 10 10 0 10 10 19 0 0 0 0 0 10 46 37 % K
% Leu: 10 37 0 0 10 0 10 0 10 10 0 19 37 0 0 % L
% Met: 0 0 0 10 0 0 0 10 0 0 0 10 0 0 0 % M
% Asn: 0 0 10 10 10 0 0 0 0 0 0 10 0 0 10 % N
% Pro: 10 10 0 10 19 10 0 10 46 0 10 0 19 10 0 % P
% Gln: 10 0 0 0 0 0 0 0 10 0 0 0 10 0 0 % Q
% Arg: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 19 % R
% Ser: 0 0 46 0 0 0 0 10 10 64 55 0 19 10 0 % S
% Thr: 10 10 10 46 37 0 10 46 0 10 10 0 0 10 0 % T
% Val: 0 0 10 0 10 46 0 10 19 0 0 0 0 19 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _