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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTS All Species: 13.33
Human Site: S19 Identified Species: 26.67
UniProt: Q03393 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03393 NP_000308.1 145 16386 S19 A Q V S R R I S F S A S H R L
Chimpanzee Pan troglodytes XP_001147929 145 16309 S19 A K V S R R I S F S A S H R L
Rhesus Macaque Macaca mulatta XP_001108264 145 16335 S19 A Q V S R R I S F S A S H R L
Dog Lupus familis XP_854076 150 16605 S24 A R V S R L V S F S A T H R L
Cat Felis silvestris
Mouse Mus musculus Q9R1Z7 144 16170 F19 R L S R L V S F S A S H R L H
Rat Rattus norvegicus P27213 144 16222 F19 R L S R L V S F S A S H R L H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417928 148 16731 A19 S R T A S F S A C H R L H S K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001092237 139 15906 R19 C S F S A C H R L H S K C L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48611 168 19318 H19 R E T F S A C H R L H S P Q L
Honey Bee Apis mellifera XP_395481 142 16642 R19 E V I S S C H R L H N E N L T
Nematode Worm Caenorhab. elegans O02058 140 16028 H19 V D S F S A A H R L H S E K L
Sea Urchin Strong. purpuratus XP_795640 149 17138 P19 T T A T Y A R P I P Y A I R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 97.9 84 N.A. 82 82 N.A. N.A. 73.6 N.A. 68.9 N.A. 46.4 55.1 50.3 51.6
Protein Similarity: 100 99.3 98.6 91.3 N.A. 91.7 91.7 N.A. N.A. 85.8 N.A. 82 N.A. 62.5 77.9 65.5 69.8
P-Site Identity: 100 93.3 100 73.3 N.A. 0 0 N.A. N.A. 6.6 N.A. 6.6 N.A. 13.3 6.6 13.3 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 13.3 13.3 N.A. N.A. 33.3 N.A. 13.3 N.A. 26.6 20 20 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 34 0 9 9 9 25 9 9 0 17 34 9 0 0 0 % A
% Cys: 9 0 0 0 0 17 9 0 9 0 0 0 9 0 0 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 9 9 0 0 0 0 0 0 0 0 0 9 9 0 0 % E
% Phe: 0 0 9 17 0 9 0 17 34 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 17 17 0 25 17 17 42 0 17 % H
% Ile: 0 0 9 0 0 0 25 0 9 0 0 0 9 0 0 % I
% Lys: 0 9 0 0 0 0 0 0 0 0 0 9 0 9 9 % K
% Leu: 0 17 0 0 17 9 0 0 17 17 0 9 0 34 50 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 9 0 9 0 0 9 0 9 % P
% Gln: 0 17 0 0 0 0 0 0 0 0 0 0 0 9 0 % Q
% Arg: 25 17 0 17 34 25 9 17 17 0 9 0 17 42 0 % R
% Ser: 9 9 25 50 34 0 25 34 17 34 25 42 0 9 9 % S
% Thr: 9 9 17 9 0 0 0 0 0 0 0 9 0 0 9 % T
% Val: 9 9 34 0 0 17 9 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _