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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTS All Species: 43.64
Human Site: Y53 Identified Species: 87.27
UniProt: Q03393 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03393 NP_000308.1 145 16386 Y53 P N G H G H N Y K V V V T V H
Chimpanzee Pan troglodytes XP_001147929 145 16309 Y53 P N G H G H N Y K V V V T V H
Rhesus Macaque Macaca mulatta XP_001108264 145 16335 Y53 P N G H G H N Y K V V V T V H
Dog Lupus familis XP_854076 150 16605 Y58 P N G H G H N Y K V V V T V H
Cat Felis silvestris
Mouse Mus musculus Q9R1Z7 144 16170 Y52 P N G H G H N Y K V V V T V H
Rat Rattus norvegicus P27213 144 16222 Y52 P N G H G H N Y K V V V T I H
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_417928 148 16731 Y50 P N G H G H N Y K V I V T V R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001092237 139 15906 Y47 P N G H G H N Y T V E V T V R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P48611 168 19318 Y48 F H G H G H N Y T V E I T V R
Honey Bee Apis mellifera XP_395481 142 16642 Y47 Y W G H G H N Y T V E V T V C
Nematode Worm Caenorhab. elegans O02058 140 16028 Y48 S N G H G H N Y V W K V K L R
Sea Urchin Strong. purpuratus XP_795640 149 17138 Y56 P N G H G H N Y K V E L T L R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 97.9 84 N.A. 82 82 N.A. N.A. 73.6 N.A. 68.9 N.A. 46.4 55.1 50.3 51.6
Protein Similarity: 100 99.3 98.6 91.3 N.A. 91.7 91.7 N.A. N.A. 85.8 N.A. 82 N.A. 62.5 77.9 65.5 69.8
P-Site Identity: 100 100 100 100 N.A. 100 93.3 N.A. N.A. 86.6 N.A. 80 N.A. 60 66.6 53.3 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 93.3 N.A. 80 N.A. 73.3 66.6 60 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 34 0 0 0 0 % E
% Phe: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 100 0 100 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 9 0 100 0 100 0 0 0 0 0 0 0 0 50 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 9 9 0 9 0 % I
% Lys: 0 0 0 0 0 0 0 0 67 0 9 0 9 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 9 0 17 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 84 0 0 0 0 100 0 0 0 0 0 0 0 0 % N
% Pro: 75 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 42 % R
% Ser: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 25 0 0 0 92 0 0 % T
% Val: 0 0 0 0 0 0 0 0 9 92 50 84 0 75 0 % V
% Trp: 0 9 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 100 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _