Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MVK All Species: 19.39
Human Site: S128 Identified Species: 42.67
UniProt: Q03426 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03426 NP_000422.1 396 42451 S128 R K Q R A L P S L D I V V W S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105759 396 42516 S128 R K Q R A L P S L D I V V W S
Dog Lupus familis XP_543435 409 43821 S141 R K Q R T L P S L D I T V W S
Cat Felis silvestris
Mouse Mus musculus Q9R008 395 41859 S128 R K Q R T L P S L D M V V W S
Rat Rattus norvegicus P17256 395 41969 S128 R K Q R T L P S L D I M V W S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231562 527 56812 A151 S L R V A A G A C L K P R R S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007350 396 42696 S127 V F A E S L A S I T V S V W S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001022867 614 66051 A268 H R K R D L L A V K A T V R F
Sea Urchin Strong. purpuratus XP_790690 413 45125 I138 G R N G K F P I L D T L V S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46086 378 40625 P131 T R I I G F N P A T V V I N S
Baker's Yeast Sacchar. cerevisiae P07277 443 48441 N131 C L C P H A K N I K F S L K S
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.2 81.9 N.A. 81 81.8 N.A. N.A. 28.6 N.A. 56.5 N.A. N.A. N.A. 27.5 46
Protein Similarity: 100 N.A. 96.7 87.5 N.A. 88.1 90.1 N.A. N.A. 41.7 N.A. 73.9 N.A. N.A. N.A. 39 63.4
P-Site Identity: 100 N.A. 100 86.6 N.A. 86.6 86.6 N.A. N.A. 13.3 N.A. 33.3 N.A. N.A. N.A. 20 33.3
P-Site Similarity: 100 N.A. 100 86.6 N.A. 93.3 93.3 N.A. N.A. 26.6 N.A. 53.3 N.A. N.A. N.A. 46.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. 36.6 32.7 N.A.
Protein Similarity: N.A. N.A. N.A. 57.5 53.2 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 28 19 10 19 10 0 10 0 0 0 0 % A
% Cys: 10 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 0 0 0 0 55 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 0 19 0 0 0 0 10 0 0 0 10 % F
% Gly: 10 0 0 10 10 0 10 0 0 0 0 0 0 0 0 % G
% His: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 10 0 0 0 10 19 0 37 0 10 0 0 % I
% Lys: 0 46 10 0 10 0 10 0 0 19 10 0 0 10 0 % K
% Leu: 0 19 0 0 0 64 10 0 55 10 0 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % M
% Asn: 0 0 10 0 0 0 10 10 0 0 0 0 0 10 0 % N
% Pro: 0 0 0 10 0 0 55 10 0 0 0 10 0 0 0 % P
% Gln: 0 0 46 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 46 28 10 55 0 0 0 0 0 0 0 0 10 19 0 % R
% Ser: 10 0 0 0 10 0 0 55 0 0 0 19 0 10 91 % S
% Thr: 10 0 0 0 28 0 0 0 0 19 10 19 0 0 0 % T
% Val: 10 0 0 10 0 0 0 0 10 0 19 37 73 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 55 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _