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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MVK
All Species:
1.21
Human Site:
S227
Identified Species:
2.67
UniProt:
Q03426
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03426
NP_000422.1
396
42451
S227
K
I
S
S
L
K
R
S
P
A
L
Q
I
L
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105759
396
42516
P227
K
I
S
S
L
K
R
P
P
A
L
Q
I
L
L
Dog
Lupus familis
XP_543435
409
43821
L240
K
I
S
S
I
K
R
L
P
A
L
K
I
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9R008
395
41859
L227
T
M
S
S
L
K
S
L
P
S
L
Q
I
L
L
Rat
Rattus norvegicus
P17256
395
41969
L227
K
M
S
S
L
K
R
L
P
A
L
Q
I
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231562
527
56812
D329
A
I
S
A
K
Y
G
D
V
P
S
V
D
I
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007350
396
42696
V226
N
I
T
P
L
S
W
V
P
I
L
R
I
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001022867
614
66051
L370
R
I
E
H
L
K
N
L
P
D
L
R
V
I
L
Sea Urchin
Strong. purpuratus
XP_790690
413
45125
M236
V
I
T
P
L
E
N
M
P
E
L
S
I
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46086
378
40625
N227
E
I
T
R
L
Q
S
N
M
P
L
R
M
L
I
Baker's Yeast
Sacchar. cerevisiae
P07277
443
48441
T225
S
H
N
G
T
I
N
T
N
N
F
K
F
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.2
81.9
N.A.
81
81.8
N.A.
N.A.
28.6
N.A.
56.5
N.A.
N.A.
N.A.
27.5
46
Protein Similarity:
100
N.A.
96.7
87.5
N.A.
88.1
90.1
N.A.
N.A.
41.7
N.A.
73.9
N.A.
N.A.
N.A.
39
63.4
P-Site Identity:
100
N.A.
93.3
80
N.A.
66.6
86.6
N.A.
N.A.
13.3
N.A.
46.6
N.A.
N.A.
N.A.
40
46.6
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
80
93.3
N.A.
N.A.
26.6
N.A.
60
N.A.
N.A.
N.A.
66.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
32.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.5
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
0
37
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
10
0
0
10
0
10
% D
% Glu:
10
0
10
0
0
10
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% F
% Gly:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
0
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
73
0
0
10
10
0
0
0
10
0
0
64
19
10
% I
% Lys:
37
0
0
0
10
55
0
0
0
0
0
19
0
0
0
% K
% Leu:
0
0
0
0
73
0
0
37
0
0
82
0
0
82
73
% L
% Met:
0
19
0
0
0
0
0
10
10
0
0
0
10
0
0
% M
% Asn:
10
0
10
0
0
0
28
10
10
10
0
0
0
0
0
% N
% Pro:
0
0
0
19
0
0
0
10
73
19
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
37
0
0
0
% Q
% Arg:
10
0
0
10
0
0
37
0
0
0
0
28
0
0
0
% R
% Ser:
10
0
55
46
0
10
19
10
0
10
10
10
0
0
0
% S
% Thr:
10
0
28
0
10
0
0
10
0
0
0
0
0
0
0
% T
% Val:
10
0
0
0
0
0
0
10
10
0
0
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _