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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MVK
All Species:
22.73
Human Site:
S381
Identified Species:
50
UniProt:
Q03426
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03426
NP_000422.1
396
42451
S381
A
P
G
V
S
I
H
S
A
T
S
L
D
S
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105759
396
42516
S381
A
P
G
V
S
I
H
S
A
T
S
L
D
S
R
Dog
Lupus familis
XP_543435
409
43821
S394
A
P
G
I
S
I
H
S
A
A
S
L
D
T
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9R008
395
41859
S381
A
P
G
V
S
T
H
S
A
A
A
V
G
D
P
Rat
Rattus norvegicus
P17256
395
41969
S381
A
P
G
V
S
M
H
S
A
T
S
I
E
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231562
527
56812
S512
A
P
G
V
T
L
H
S
S
S
A
L
N
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007350
396
42696
S381
A
P
G
V
Q
Q
H
S
S
A
A
I
S
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001022867
614
66051
Q591
G
P
G
V
V
E
H
Q
T
R
P
E
L
F
Q
Sea Urchin
Strong. purpuratus
XP_790690
413
45125
R393
A
H
G
V
M
M
H
R
S
K
E
T
L
L
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46086
378
40625
C364
L
E
S
S
G
F
Q
C
F
T
A
L
I
G
G
Baker's Yeast
Sacchar. cerevisiae
P07277
443
48441
L399
G
G
T
G
C
C
L
L
S
A
K
N
L
N
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.2
81.9
N.A.
81
81.8
N.A.
N.A.
28.6
N.A.
56.5
N.A.
N.A.
N.A.
27.5
46
Protein Similarity:
100
N.A.
96.7
87.5
N.A.
88.1
90.1
N.A.
N.A.
41.7
N.A.
73.9
N.A.
N.A.
N.A.
39
63.4
P-Site Identity:
100
N.A.
100
73.3
N.A.
53.3
66.6
N.A.
N.A.
46.6
N.A.
40
N.A.
N.A.
N.A.
26.6
26.6
P-Site Similarity:
100
N.A.
100
93.3
N.A.
66.6
86.6
N.A.
N.A.
93.3
N.A.
60
N.A.
N.A.
N.A.
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
32.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.5
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
73
0
0
0
0
0
0
0
46
37
37
0
0
10
0
% A
% Cys:
0
0
0
0
10
10
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
28
19
10
% D
% Glu:
0
10
0
0
0
10
0
0
0
0
10
10
10
0
10
% E
% Phe:
0
0
0
0
0
10
0
0
10
0
0
0
0
10
0
% F
% Gly:
19
10
82
10
10
0
0
0
0
0
0
0
10
10
19
% G
% His:
0
10
0
0
0
0
82
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
0
28
0
0
0
0
0
19
10
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
10
% K
% Leu:
10
0
0
0
0
10
10
10
0
0
0
46
28
10
0
% L
% Met:
0
0
0
0
10
19
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
10
10
0
% N
% Pro:
0
73
0
0
0
0
0
0
0
0
10
0
0
10
19
% P
% Gln:
0
0
0
0
10
10
10
10
0
0
0
0
0
0
19
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
19
% R
% Ser:
0
0
10
10
46
0
0
64
37
10
37
0
10
19
0
% S
% Thr:
0
0
10
0
10
10
0
0
10
37
0
10
0
10
0
% T
% Val:
0
0
0
73
10
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _