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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MVK All Species: 4.85
Human Site: S85 Identified Species: 10.67
UniProt: Q03426 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03426 NP_000422.1 396 42451 S85 G D V T T P T S E Q V E K L K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105759 396 42516 P85 G D A T T P T P E L V E K L K
Dog Lupus familis XP_543435 409 43821 A94 G N A T G D A A A P T S E Q V
Cat Felis silvestris
Mouse Mus musculus Q9R008 395 41859 L85 G D V S V P T L E Q L E K L K
Rat Rattus norvegicus P17256 395 41969 L85 G D V P A P T L E Q L E K L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231562 527 56812 G107 E N L I L D L G G Y T E L V D
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007350 396 42696 A86 R D P K E L D A D L L K K L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001022867 614 66051 L224 E E D Q P P S L E I L V P I A
Sea Urchin Strong. purpuratus XP_790690 413 45125 S95 D V M E V K P S V E I M Q R L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46086 378 40625 S87 L C R S T P A S C S E E T L K
Baker's Yeast Sacchar. cerevisiae P07277 443 48441 T88 L A K A Q Q A T D G L S Q E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.2 81.9 N.A. 81 81.8 N.A. N.A. 28.6 N.A. 56.5 N.A. N.A. N.A. 27.5 46
Protein Similarity: 100 N.A. 96.7 87.5 N.A. 88.1 90.1 N.A. N.A. 41.7 N.A. 73.9 N.A. N.A. N.A. 39 63.4
P-Site Identity: 100 N.A. 80 13.3 N.A. 73.3 73.3 N.A. N.A. 6.6 N.A. 20 N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: 100 N.A. 80 33.3 N.A. 86.6 80 N.A. N.A. 26.6 N.A. 53.3 N.A. N.A. N.A. 40 33.3
Percent
Protein Identity: N.A. N.A. N.A. 36.6 32.7 N.A.
Protein Similarity: N.A. N.A. N.A. 57.5 53.2 N.A.
P-Site Identity: N.A. N.A. N.A. 40 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 19 10 10 0 28 19 10 0 0 0 0 0 10 % A
% Cys: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 10 46 10 0 0 19 10 0 19 0 0 0 0 0 10 % D
% Glu: 19 10 0 10 10 0 0 0 46 10 10 55 10 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 46 0 0 0 10 0 0 10 10 10 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 10 10 0 0 10 0 % I
% Lys: 0 0 10 10 0 10 0 0 0 0 0 10 46 0 46 % K
% Leu: 19 0 10 0 10 10 10 28 0 19 46 0 10 55 19 % L
% Met: 0 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % M
% Asn: 0 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 10 10 10 55 10 10 0 10 0 0 10 0 0 % P
% Gln: 0 0 0 10 10 10 0 0 0 28 0 0 19 10 0 % Q
% Arg: 10 0 10 0 0 0 0 0 0 0 0 0 0 10 10 % R
% Ser: 0 0 0 19 0 0 10 28 0 10 0 19 0 0 0 % S
% Thr: 0 0 0 28 28 0 37 10 0 0 19 0 10 0 0 % T
% Val: 0 10 28 0 19 0 0 0 10 0 19 10 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _