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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MVK
All Species:
13.94
Human Site:
T178
Identified Species:
30.67
UniProt:
Q03426
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03426
NP_000422.1
396
42451
T178
G
D
C
V
N
R
W
T
K
E
D
L
E
L
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105759
396
42516
T178
G
D
R
V
N
R
W
T
K
E
D
L
E
L
I
Dog
Lupus familis
XP_543435
409
43821
T191
G
E
S
A
S
R
W
T
M
E
D
L
E
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9R008
395
41859
P178
G
V
S
V
S
R
W
P
E
E
D
L
K
S
I
Rat
Rattus norvegicus
P17256
395
41969
P178
R
G
S
I
G
S
W
P
E
E
D
L
K
S
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231562
527
56812
G288
F
D
E
S
K
S
P
G
V
E
Q
L
D
V
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007350
396
42696
S177
Q
Q
E
S
A
R
W
S
K
D
E
M
E
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001022867
614
66051
E320
E
Q
G
N
L
T
W
E
E
D
H
L
D
I
I
Sea Urchin
Strong. purpuratus
XP_790690
413
45125
S187
S
D
N
T
L
D
W
S
R
E
D
M
E
L
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46086
378
40625
D178
G
N
G
W
S
S
L
D
E
T
N
L
E
L
L
Baker's Yeast
Sacchar. cerevisiae
P07277
443
48441
D179
L
E
K
L
S
E
N
D
K
H
I
V
N
Q
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.2
81.9
N.A.
81
81.8
N.A.
N.A.
28.6
N.A.
56.5
N.A.
N.A.
N.A.
27.5
46
Protein Similarity:
100
N.A.
96.7
87.5
N.A.
88.1
90.1
N.A.
N.A.
41.7
N.A.
73.9
N.A.
N.A.
N.A.
39
63.4
P-Site Identity:
100
N.A.
93.3
66.6
N.A.
53.3
33.3
N.A.
N.A.
20
N.A.
40
N.A.
N.A.
N.A.
20
46.6
P-Site Similarity:
100
N.A.
93.3
80
N.A.
73.3
53.3
N.A.
N.A.
40
N.A.
66.6
N.A.
N.A.
N.A.
46.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
32.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.5
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
37
0
0
0
10
0
19
0
19
55
0
19
0
0
% D
% Glu:
10
19
19
0
0
10
0
10
37
64
10
0
55
0
0
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
46
10
19
0
10
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
10
0
0
10
73
% I
% Lys:
0
0
10
0
10
0
0
0
37
0
0
0
19
0
0
% K
% Leu:
10
0
0
10
19
0
10
0
0
0
0
73
0
55
19
% L
% Met:
0
0
0
0
0
0
0
0
10
0
0
19
0
0
0
% M
% Asn:
0
10
10
10
19
0
10
0
0
0
10
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
10
19
0
0
0
0
0
0
0
% P
% Gln:
10
19
0
0
0
0
0
0
0
0
10
0
0
10
0
% Q
% Arg:
10
0
10
0
0
46
0
0
10
0
0
0
0
0
0
% R
% Ser:
10
0
28
19
37
28
0
19
0
0
0
0
0
19
0
% S
% Thr:
0
0
0
10
0
10
0
28
0
10
0
0
0
0
0
% T
% Val:
0
10
0
28
0
0
0
0
10
0
0
10
0
10
0
% V
% Trp:
0
0
0
10
0
0
73
0
0
0
0
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _