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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MVK All Species: 23.94
Human Site: T322 Identified Species: 52.67
UniProt: Q03426 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03426 NP_000422.1 396 42451 T322 L D Q L C Q V T R A R G L H S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105759 396 42516 T322 L D Q L C Q V T R A H G L H S
Dog Lupus familis XP_543435 409 43821 T335 L D Q L C Q V T M A H G L H S
Cat Felis silvestris
Mouse Mus musculus Q9R008 395 41859 T322 L D Q L C Q V T A A H G L H S
Rat Rattus norvegicus P17256 395 41969 T322 L D Q L C Q V T A A H G L H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231562 527 56812 T453 L D R L C R V T A S H G L H S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007350 396 42696 T322 L D T L C R V T L S K G L H S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001022867 614 66051 L532 V D L I C T T L A R Y G I H P
Sea Urchin Strong. purpuratus XP_790690 413 45125 A334 I N N I V R S A A A Y K I H A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46086 378 40625 L305 M E M N Q G L L L S M G V S H
Baker's Yeast Sacchar. cerevisiae P07277 443 48441 D340 E L I K N L S D D L R I G S T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.2 81.9 N.A. 81 81.8 N.A. N.A. 28.6 N.A. 56.5 N.A. N.A. N.A. 27.5 46
Protein Similarity: 100 N.A. 96.7 87.5 N.A. 88.1 90.1 N.A. N.A. 41.7 N.A. 73.9 N.A. N.A. N.A. 39 63.4
P-Site Identity: 100 N.A. 93.3 86.6 N.A. 86.6 86.6 N.A. N.A. 66.6 N.A. 66.6 N.A. N.A. N.A. 26.6 13.3
P-Site Similarity: 100 N.A. 93.3 86.6 N.A. 86.6 86.6 N.A. N.A. 86.6 N.A. 86.6 N.A. N.A. N.A. 46.6 53.3
Percent
Protein Identity: N.A. N.A. N.A. 36.6 32.7 N.A.
Protein Similarity: N.A. N.A. N.A. 57.5 53.2 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 10 46 55 0 0 0 0 10 % A
% Cys: 0 0 0 0 73 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 73 0 0 0 0 0 10 10 0 0 0 0 0 0 % D
% Glu: 10 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 10 0 0 0 0 0 82 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 46 0 0 82 10 % H
% Ile: 10 0 10 19 0 0 0 0 0 0 0 10 19 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 10 10 0 0 0 % K
% Leu: 64 10 10 64 0 10 10 19 19 10 0 0 64 0 0 % L
% Met: 10 0 10 0 0 0 0 0 10 0 10 0 0 0 0 % M
% Asn: 0 10 10 10 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % P
% Gln: 0 0 46 0 10 46 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 10 0 0 28 0 0 19 10 19 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 19 0 0 28 0 0 0 19 64 % S
% Thr: 0 0 10 0 0 10 10 64 0 0 0 0 0 0 10 % T
% Val: 10 0 0 0 10 0 64 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 19 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _