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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MVK All Species: 36.97
Human Site: T332 Identified Species: 81.33
UniProt: Q03426 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03426 NP_000422.1 396 42451 T332 R G L H S K L T G A G G G G C
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001105759 396 42516 T332 H G L H S K L T G A G G G G C
Dog Lupus familis XP_543435 409 43821 T345 H G L H S K L T G A G G G G C
Cat Felis silvestris
Mouse Mus musculus Q9R008 395 41859 T332 H G L H S K L T G A G G G G C
Rat Rattus norvegicus P17256 395 41969 T332 H G L H S K L T G A G G G G C
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001231562 527 56812 T463 H G L H S K L T G A G G G G C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001007350 396 42696 T332 K G L H S K L T G A G G G G C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001022867 614 66051 T542 Y G I H P K M T G A G G G G S
Sea Urchin Strong. purpuratus XP_790690 413 45125 T344 Y K I H A K L T G A G G G G C
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P46086 378 40625 I315 M G V S H S S I E A V I L T T
Baker's Yeast Sacchar. cerevisiae P07277 443 48441 T350 R I G S T K L T G A G G G G C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 96.2 81.9 N.A. 81 81.8 N.A. N.A. 28.6 N.A. 56.5 N.A. N.A. N.A. 27.5 46
Protein Similarity: 100 N.A. 96.7 87.5 N.A. 88.1 90.1 N.A. N.A. 41.7 N.A. 73.9 N.A. N.A. N.A. 39 63.4
P-Site Identity: 100 N.A. 93.3 93.3 N.A. 93.3 93.3 N.A. N.A. 93.3 N.A. 93.3 N.A. N.A. N.A. 66.6 73.3
P-Site Similarity: 100 N.A. 93.3 93.3 N.A. 93.3 93.3 N.A. N.A. 93.3 N.A. 100 N.A. N.A. N.A. 80 86.6
Percent
Protein Identity: N.A. N.A. N.A. 36.6 32.7 N.A.
Protein Similarity: N.A. N.A. N.A. 57.5 53.2 N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 73.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 100 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 82 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 82 10 0 0 0 0 0 91 0 91 91 91 91 0 % G
% His: 46 0 0 82 10 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 10 19 0 0 0 0 10 0 0 0 10 0 0 0 % I
% Lys: 10 10 0 0 0 91 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 64 0 0 0 82 0 0 0 0 0 10 0 0 % L
% Met: 10 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 19 64 10 10 0 0 0 0 0 0 0 10 % S
% Thr: 0 0 0 0 10 0 0 91 0 0 0 0 0 10 10 % T
% Val: 0 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _