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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MVK
All Species:
20
Human Site:
Y216
Identified Species:
44
UniProt:
Q03426
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03426
NP_000422.1
396
42451
Y216
T
W
G
G
A
L
R
Y
H
Q
G
K
I
S
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001105759
396
42516
Y216
T
W
G
G
A
L
R
Y
Q
Q
G
K
I
S
S
Dog
Lupus familis
XP_543435
409
43821
Y229
T
W
G
G
A
L
R
Y
Q
Q
G
K
I
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9R008
395
41859
F216
T
W
G
G
A
L
R
F
Q
Q
G
T
M
S
S
Rat
Rattus norvegicus
P17256
395
41969
Y216
T
W
G
G
A
L
R
Y
Q
Q
G
K
M
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001231562
527
56812
Y318
L
A
I
L
A
F
L
Y
M
C
L
A
I
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001007350
396
42696
Y215
T
W
G
G
F
L
R
Y
H
S
G
N
I
T
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001022867
614
66051
K359
F
G
G
V
A
S
F
K
P
G
H
R
I
E
H
Sea Urchin
Strong. purpuratus
XP_790690
413
45125
Y225
V
H
G
G
A
I
E
Y
R
Q
K
V
I
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P46086
378
40625
F216
A
Y
G
N
M
I
K
F
C
S
G
E
I
T
R
Baker's Yeast
Sacchar. cerevisiae
P07277
443
48441
F214
T
Y
G
N
A
L
L
F
E
K
D
S
H
N
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
96.2
81.9
N.A.
81
81.8
N.A.
N.A.
28.6
N.A.
56.5
N.A.
N.A.
N.A.
27.5
46
Protein Similarity:
100
N.A.
96.7
87.5
N.A.
88.1
90.1
N.A.
N.A.
41.7
N.A.
73.9
N.A.
N.A.
N.A.
39
63.4
P-Site Identity:
100
N.A.
93.3
93.3
N.A.
73.3
86.6
N.A.
N.A.
26.6
N.A.
66.6
N.A.
N.A.
N.A.
20
40
P-Site Similarity:
100
N.A.
93.3
93.3
N.A.
86.6
93.3
N.A.
N.A.
33.3
N.A.
73.3
N.A.
N.A.
N.A.
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.6
32.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.5
53.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
0
82
0
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
10
0
10
0
0
10
0
10
0
% E
% Phe:
10
0
0
0
10
10
10
28
0
0
0
0
0
0
0
% F
% Gly:
0
10
91
64
0
0
0
0
0
10
64
0
0
0
10
% G
% His:
0
10
0
0
0
0
0
0
19
0
10
0
10
0
10
% H
% Ile:
0
0
10
0
0
19
0
0
0
0
0
0
73
0
0
% I
% Lys:
0
0
0
0
0
0
10
10
0
10
10
37
0
0
0
% K
% Leu:
10
0
0
10
0
64
19
0
0
0
10
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
10
0
0
0
19
0
0
% M
% Asn:
0
0
0
19
0
0
0
0
0
0
0
10
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
19
% P
% Gln:
0
0
0
0
0
0
0
0
37
55
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
55
0
10
0
0
10
0
0
10
% R
% Ser:
0
0
0
0
0
10
0
0
0
19
0
10
0
55
46
% S
% Thr:
64
0
0
0
0
0
0
0
0
0
0
10
0
28
0
% T
% Val:
10
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
55
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
0
0
64
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _