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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTH1R All Species: 4.55
Human Site: S61 Identified Species: 14.29
UniProt: Q03431 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03431 NP_000307.1 593 66361 S61 E V L Q R P A S I M E S D K G
Chimpanzee Pan troglodytes XP_001152178 593 66339 N61 E V L Q R P A N I M E S D K G
Rhesus Macaque Macaca mulatta XP_001113857 593 66366 S61 E V L Q R P A S I M E S D K G
Dog Lupus familis XP_541003 444 50308
Cat Felis silvestris
Mouse Mus musculus P41593 591 66295 N61 E V L H T A A N I M E S D K G
Rat Rattus norvegicus P25961 591 66242 N61 E V L H T A A N I M E S D K G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001171046 538 61211 A28 S V Y A L V D A D D V I T K E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_571432 536 61436 L25 L L S F V Y G L V D A D D V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.9 35.5 N.A. 89.8 90.3 N.A. N.A. 71.1 N.A. 63.7 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.8 99.3 49 N.A. 93.7 93.9 N.A. N.A. 80.4 N.A. 74.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 0 N.A. 73.3 73.3 N.A. N.A. 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 0 N.A. 80 80 N.A. N.A. 20 N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 13 0 25 63 13 0 0 13 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 13 0 13 25 0 13 75 0 0 % D
% Glu: 63 0 0 0 0 0 0 0 0 0 63 0 0 0 13 % E
% Phe: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 63 % G
% His: 0 0 0 25 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 63 0 0 13 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 75 0 % K
% Leu: 13 13 63 0 13 0 0 13 0 0 0 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 63 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 38 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 38 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 38 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 38 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 13 0 13 0 0 0 0 25 0 0 0 63 0 0 0 % S
% Thr: 0 0 0 0 25 0 0 0 0 0 0 0 13 0 0 % T
% Val: 0 75 0 0 13 13 0 0 13 0 13 0 0 13 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 13 0 0 13 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _