KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERCC6
All Species:
14.85
Human Site:
S552
Identified Species:
27.22
UniProt:
Q03468
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03468
NP_000115.1
1493
168416
S552
F
L
A
G
L
S
Y
S
K
I
R
T
R
G
S
Chimpanzee
Pan troglodytes
XP_507781
1491
168031
S550
F
L
A
G
L
S
Y
S
K
I
R
T
R
G
S
Rhesus Macaque
Macaca mulatta
XP_001107536
1496
168876
S555
F
L
A
G
L
S
Y
S
K
I
R
T
R
G
S
Dog
Lupus familis
XP_534944
1486
168108
S548
F
L
A
G
L
S
Y
S
K
I
R
T
R
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
NP_001100766
1325
148468
Y434
D
D
G
D
E
D
Y
Y
K
Q
R
L
R
R
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508174
968
109820
I77
R
A
D
S
S
R
G
I
W
E
F
G
V
V
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24368
1027
118855
G135
M
R
D
Y
Q
I
R
G
L
N
W
M
I
S
L
Honey Bee
Apis mellifera
XP_001120586
932
107557
N41
I
I
T
K
G
T
F
N
K
S
S
C
L
L
D
Nematode Worm
Caenorhab. elegans
P41877
1009
116656
V118
A
I
K
S
D
D
L
V
I
F
D
K
S
P
F
Sea Urchin
Strong. purpuratus
XP_001193315
953
107227
C62
L
G
P
V
L
I
V
C
P
A
T
V
L
H
Q
Poplar Tree
Populus trichocarpa
XP_002307656
1206
134941
P313
P
L
K
A
C
Q
S
P
E
R
D
A
E
K
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RWY3
1057
122611
E166
D
E
E
Y
L
K
E
E
E
D
G
L
T
G
S
Baker's Yeast
Sacchar. cerevisiae
P40352
1085
124509
E194
M
V
E
N
L
T
D
E
D
D
N
L
S
D
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
97.2
83.3
N.A.
N.A.
70.1
N.A.
44.6
N.A.
N.A.
N.A.
N.A.
20
31.4
20.6
36.4
Protein Similarity:
100
99.4
97.9
89.1
N.A.
N.A.
76.4
N.A.
52.2
N.A.
N.A.
N.A.
N.A.
35.7
43.8
35.7
45.8
P-Site Identity:
100
100
100
100
N.A.
N.A.
26.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
6.6
0
6.6
P-Site Similarity:
100
100
100
100
N.A.
N.A.
26.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
33.3
6.6
6.6
Percent
Protein Identity:
29.4
N.A.
N.A.
23.5
28.4
N.A.
Protein Similarity:
44.9
N.A.
N.A.
38.2
43.9
N.A.
P-Site Identity:
6.6
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
26.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
31
8
0
0
0
0
0
8
0
8
0
0
8
% A
% Cys:
0
0
0
0
8
0
0
8
0
0
0
8
0
0
0
% C
% Asp:
16
8
16
8
8
16
8
0
8
16
16
0
0
8
8
% D
% Glu:
0
8
16
0
8
0
8
16
16
8
0
0
8
0
0
% E
% Phe:
31
0
0
0
0
0
8
0
0
8
8
0
0
0
8
% F
% Gly:
0
8
8
31
8
0
8
8
0
0
8
8
0
39
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
8
16
0
0
0
16
0
8
8
31
0
0
8
0
0
% I
% Lys:
0
0
16
8
0
8
0
0
47
0
0
8
0
8
0
% K
% Leu:
8
39
0
0
54
0
8
0
8
0
0
24
16
8
8
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
8
8
0
0
0
0
% N
% Pro:
8
0
8
0
0
0
0
8
8
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
8
8
0
0
0
8
0
0
0
0
16
% Q
% Arg:
8
8
0
0
0
8
8
0
0
8
39
0
39
8
8
% R
% Ser:
0
0
0
16
8
31
8
31
0
8
8
0
16
8
39
% S
% Thr:
0
0
8
0
0
16
0
0
0
0
8
31
8
0
0
% T
% Val:
0
8
0
8
0
0
8
8
0
0
0
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
8
0
0
0
8
% W
% Tyr:
0
0
0
16
0
0
39
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _