Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAP1 All Species: 10.91
Human Site: S551 Identified Species: 21.82
UniProt: Q03518 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03518 NP_000584.2 808 87218 S551 R T P R C P P S G L L T P L H
Chimpanzee Pan troglodytes XP_527356 808 87199 S551 R T P R C P P S G L L T P L H
Rhesus Macaque Macaca mulatta XP_001115506 808 86981 S551 R T P R C P P S G L L T P L H
Dog Lupus familis XP_532101 505 55747 V273 A Y P N H P D V P V L Q A L T
Cat Felis silvestris
Mouse Mus musculus P21958 724 78987 N490 D V S F A Y P N Q P K V Q V L
Rat Rattus norvegicus P36370 725 79132 P493 S F A Y P N H P N V Q V L Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415125 794 87190 T537 T L H P G K V T A L V G P S G
Frog Xenopus laevis NP_001165360 726 80978 Q493 R P D S L V L Q D V S F E L H
Zebra Danio Brachydanio rerio Q56A55 714 77317 R482 I S F S Y P T R P G N Q I L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00748 1302 143766 N1047 S P M G T I K N T L A K Q L N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34712 1321 145045 S1065 I S K I D S L S L A G E K K K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WML0 644 69085 M412 Y P S R P S H M I L K G I S L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 94.8 49.7 N.A. 65.3 65.5 N.A. N.A. 34.4 41.5 28.2 N.A. 22.6 N.A. 23 N.A.
Protein Similarity: 100 99 97.1 55.6 N.A. 74.3 76.2 N.A. N.A. 55.5 57.2 47.5 N.A. 36.7 N.A. 35.7 N.A.
P-Site Identity: 100 100 100 26.6 N.A. 6.6 0 N.A. N.A. 13.3 20 13.3 N.A. 13.3 N.A. 6.6 N.A.
P-Site Similarity: 100 100 100 33.3 N.A. 20 6.6 N.A. N.A. 26.6 26.6 20 N.A. 26.6 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 46 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 9 0 0 0 9 9 9 0 9 0 0 % A
% Cys: 0 0 0 0 25 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 9 0 9 0 9 0 9 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % E
% Phe: 0 9 9 9 0 0 0 0 0 0 0 9 0 0 0 % F
% Gly: 0 0 0 9 9 0 0 0 25 9 9 17 0 0 17 % G
% His: 0 0 9 0 9 0 17 0 0 0 0 0 0 0 34 % H
% Ile: 17 0 0 9 0 9 0 0 9 0 0 0 17 0 0 % I
% Lys: 0 0 9 0 0 9 9 0 0 0 17 9 9 9 17 % K
% Leu: 0 9 0 0 9 0 17 0 9 50 34 0 9 59 17 % L
% Met: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 9 0 17 9 0 9 0 0 0 9 % N
% Pro: 0 25 34 9 17 42 34 9 17 9 0 0 34 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 9 0 9 17 17 9 0 % Q
% Arg: 34 0 0 34 0 0 0 9 0 0 0 0 0 0 0 % R
% Ser: 17 17 17 17 0 17 0 34 0 0 9 0 0 17 0 % S
% Thr: 9 25 0 0 9 0 9 9 9 0 0 25 0 0 9 % T
% Val: 0 9 0 0 0 9 9 9 0 25 9 17 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 9 9 0 9 9 9 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _