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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAP1 All Species: 10.91
Human Site: T285 Identified Species: 21.82
UniProt: Q03518 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03518 NP_000584.2 808 87218 T285 D G S A D T F T R N L T L M S
Chimpanzee Pan troglodytes XP_527356 808 87199 T285 D G S A D T F T R N L T L M S
Rhesus Macaque Macaca mulatta XP_001115506 808 86981 T285 D G S A D T F T R N L T L M S
Dog Lupus familis XP_532101 505 55747 T12 T A S W V V C T A R C R E R Y
Cat Felis silvestris
Mouse Mus musculus P21958 724 78987 M229 D G I Y N I T M G H M H G R V
Rat Rattus norvegicus P36370 725 79132 H232 I Y N I T M G H M H S R V H G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_415125 794 87190 S270 L R N C L F R S L M S Q E M S
Frog Xenopus laevis NP_001165360 726 80978 Q232 S M I H I R T Q G Q L L R S I
Zebra Danio Brachydanio rerio Q56A55 714 77317 V221 L S R V G E R V A A D M R T T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00748 1302 143766 L775 A L R R T A V L S W A C L G L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34712 1321 145045 W796 F L S Q G H F W A L M F L V L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q0WML0 644 69085 R151 A S E R V V A R L R K D L F R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.3 94.8 49.7 N.A. 65.3 65.5 N.A. N.A. 34.4 41.5 28.2 N.A. 22.6 N.A. 23 N.A.
Protein Similarity: 100 99 97.1 55.6 N.A. 74.3 76.2 N.A. N.A. 55.5 57.2 47.5 N.A. 36.7 N.A. 35.7 N.A.
P-Site Identity: 100 100 100 13.3 N.A. 13.3 0 N.A. N.A. 13.3 6.6 0 N.A. 6.6 N.A. 20 N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 33.3 20 N.A. N.A. 26.6 6.6 6.6 N.A. 6.6 N.A. 33.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 27.7 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 46 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 6.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 0 25 0 9 9 0 25 9 9 0 0 0 0 % A
% Cys: 0 0 0 9 0 0 9 0 0 0 9 9 0 0 0 % C
% Asp: 34 0 0 0 25 0 0 0 0 0 9 9 0 0 0 % D
% Glu: 0 0 9 0 0 9 0 0 0 0 0 0 17 0 0 % E
% Phe: 9 0 0 0 0 9 34 0 0 0 0 9 0 9 0 % F
% Gly: 0 34 0 0 17 0 9 0 17 0 0 0 9 9 9 % G
% His: 0 0 0 9 0 9 0 9 0 17 0 9 0 9 0 % H
% Ile: 9 0 17 9 9 9 0 0 0 0 0 0 0 0 9 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % K
% Leu: 17 17 0 0 9 0 0 9 17 9 34 9 50 0 17 % L
% Met: 0 9 0 0 0 9 0 9 9 9 17 9 0 34 0 % M
% Asn: 0 0 17 0 9 0 0 0 0 25 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 9 0 0 0 9 0 9 0 9 0 0 0 % Q
% Arg: 0 9 17 17 0 9 17 9 25 17 0 17 17 17 9 % R
% Ser: 9 17 42 0 0 0 0 9 9 0 17 0 0 9 34 % S
% Thr: 9 0 0 0 17 25 17 34 0 0 0 25 0 9 9 % T
% Val: 0 0 0 9 17 17 9 9 0 0 0 0 9 9 9 % V
% Trp: 0 0 0 9 0 0 0 9 0 9 0 0 0 0 0 % W
% Tyr: 0 9 0 9 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _