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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAP2 All Species: 27.88
Human Site: S261 Identified Species: 61.33
UniProt: Q03519 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03519 NP_000535.3 686 75664 S261 S S D T T L M S N W L P L N A
Chimpanzee Pan troglodytes XP_509453 938 102525 S469 T S D T T M V S D L V S Q N I
Rhesus Macaque Macaca mulatta XP_001096136 907 99484 S438 T S D T T M V S D L V S Q N I
Dog Lupus familis XP_532099 791 86758 S349 S S D T K L M S C W L P L N A
Cat Felis silvestris
Mouse Mus musculus P36371 702 77426 S260 S S D T S L M S R W L P F N A
Rat Rattus norvegicus P36372 703 77695 S261 S S D T S L M S Q W L S L N A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001092827 701 75924 S259 T T D V T L A S N V L A L N I
Frog Xenopus laevis NP_001085260 714 80692 S262 T H D T A R V S R S I A A N V
Zebra Danio Brachydanio rerio Q56A55 714 77317 K261 T S D I Q E F K S S F K L V I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_491754 815 90775 S315 S A D C Q T M S N T L S L Y M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RY46 700 78020 S247 G S D C Q Q V S R V I G N D L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34 34.5 68.6 N.A. 75.6 73.8 N.A. N.A. 49.3 41.7 30.6 N.A. N.A. N.A. 32.2 N.A.
Protein Similarity: 100 47.8 49.3 75.9 N.A. 84.7 83.2 N.A. N.A. 65.3 62.6 49.4 N.A. N.A. N.A. 50.1 N.A.
P-Site Identity: 100 40 40 86.6 N.A. 80 80 N.A. N.A. 53.3 26.6 20 N.A. N.A. N.A. 46.6 N.A.
P-Site Similarity: 100 73.3 73.3 86.6 N.A. 86.6 86.6 N.A. N.A. 66.6 46.6 33.3 N.A. N.A. N.A. 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 40 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 10 0 10 0 0 0 0 19 10 0 37 % A
% Cys: 0 0 0 19 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 100 0 0 0 0 0 19 0 0 0 0 10 0 % D
% Glu: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 10 0 10 0 0 % F
% Gly: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % G
% His: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 0 0 0 0 19 0 0 0 37 % I
% Lys: 0 0 0 0 10 0 0 10 0 0 0 10 0 0 0 % K
% Leu: 0 0 0 0 0 46 0 0 0 19 55 0 55 0 10 % L
% Met: 0 0 0 0 0 19 46 0 0 0 0 0 0 0 10 % M
% Asn: 0 0 0 0 0 0 0 0 28 0 0 0 10 73 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 28 0 0 0 % P
% Gln: 0 0 0 0 28 10 0 0 10 0 0 0 19 0 0 % Q
% Arg: 0 0 0 0 0 10 0 0 28 0 0 0 0 0 0 % R
% Ser: 46 73 0 0 19 0 0 91 10 19 0 37 0 0 0 % S
% Thr: 46 10 0 64 37 10 0 0 0 10 0 0 0 0 0 % T
% Val: 0 0 0 10 0 0 37 0 0 19 19 0 0 10 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 37 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _