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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TAP2
All Species:
15.76
Human Site:
S274
Identified Species:
34.67
UniProt:
Q03519
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03519
NP_000535.3
686
75664
S274
N
A
N
V
L
L
R
S
L
V
K
V
V
G
L
Chimpanzee
Pan troglodytes
XP_509453
938
102525
N482
N
I
N
V
F
L
R
N
T
V
K
V
T
G
V
Rhesus Macaque
Macaca mulatta
XP_001096136
907
99484
N451
N
I
N
V
F
L
R
N
T
V
K
V
T
G
V
Dog
Lupus familis
XP_532099
791
86758
S362
N
A
N
V
L
L
R
S
L
V
K
V
V
G
L
Cat
Felis silvestris
Mouse
Mus musculus
P36371
702
77426
S273
N
A
N
I
L
L
R
S
L
V
K
V
V
G
L
Rat
Rattus norvegicus
P36372
703
77695
S274
N
A
N
I
L
L
R
S
L
V
K
V
V
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001092827
701
75924
N272
N
I
N
V
M
L
R
N
L
G
Q
V
L
G
L
Frog
Xenopus laevis
NP_001085260
714
80692
M275
N
V
N
I
T
L
R
M
L
V
K
C
V
G
V
Zebra Danio
Brachydanio rerio
Q56A55
714
77317
S274
V
I
S
Q
G
L
R
S
A
T
Q
T
V
G
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491754
815
90775
N328
Y
M
N
V
L
T
R
N
L
T
M
L
F
G
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8RY46
700
78020
N260
D
L
N
M
I
F
R
N
V
L
Q
G
T
G
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
34
34.5
68.6
N.A.
75.6
73.8
N.A.
N.A.
49.3
41.7
30.6
N.A.
N.A.
N.A.
32.2
N.A.
Protein Similarity:
100
47.8
49.3
75.9
N.A.
84.7
83.2
N.A.
N.A.
65.3
62.6
49.4
N.A.
N.A.
N.A.
50.1
N.A.
P-Site Identity:
100
60
60
100
N.A.
93.3
93.3
N.A.
N.A.
60
60
33.3
N.A.
N.A.
N.A.
40
N.A.
P-Site Similarity:
100
73.3
73.3
100
N.A.
100
100
N.A.
N.A.
86.6
73.3
46.6
N.A.
N.A.
N.A.
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.4
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
66.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
37
0
0
0
0
0
0
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
10
% C
% Asp:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
19
10
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
0
10
0
10
0
100
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
37
0
28
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
64
0
0
0
0
% K
% Leu:
0
10
0
0
46
82
0
0
64
10
0
10
10
0
46
% L
% Met:
0
10
0
10
10
0
0
10
0
0
10
0
0
0
0
% M
% Asn:
73
0
91
0
0
0
0
46
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
28
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
100
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
0
0
0
46
0
0
0
0
0
0
10
% S
% Thr:
0
0
0
0
10
10
0
0
19
19
0
10
28
0
0
% T
% Val:
10
10
0
55
0
0
0
0
10
64
0
64
55
0
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _