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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAP2 All Species: 30
Human Site: T246 Identified Species: 66
UniProt: Q03519 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03519 NP_000535.3 686 75664 T246 G F F Q E T K T G E L N S R L
Chimpanzee Pan troglodytes XP_509453 938 102525 T454 S F F D E N R T G D L I S R L
Rhesus Macaque Macaca mulatta XP_001096136 907 99484 T423 S F F D E N R T G D L I S R L
Dog Lupus familis XP_532099 791 86758 T334 G F F Q E T K T G E L N S R L
Cat Felis silvestris
Mouse Mus musculus P36371 702 77426 T245 G F F Q E T K T G E L N S R L
Rat Rattus norvegicus P36372 703 77695 T246 A F F Q E T K T G E L N S R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001092827 701 75924 A244 A F F Q K T T A A E L A S R L
Frog Xenopus laevis NP_001085260 714 80692 S247 A F F E D N K S G D I T S R L
Zebra Danio Brachydanio rerio Q56A55 714 77317 T246 A F F D A N K T G Q L V N R L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_491754 815 90775 T300 G F F D M N K T G E I C S R L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RY46 700 78020 V232 S F F D S Q T V G D L T S R L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34 34.5 68.6 N.A. 75.6 73.8 N.A. N.A. 49.3 41.7 30.6 N.A. N.A. N.A. 32.2 N.A.
Protein Similarity: 100 47.8 49.3 75.9 N.A. 84.7 83.2 N.A. N.A. 65.3 62.6 49.4 N.A. N.A. N.A. 50.1 N.A.
P-Site Identity: 100 60 60 100 N.A. 100 93.3 N.A. N.A. 60 46.6 53.3 N.A. N.A. N.A. 66.6 N.A.
P-Site Similarity: 100 73.3 73.3 100 N.A. 100 93.3 N.A. N.A. 66.6 80 66.6 N.A. N.A. N.A. 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 46.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 53.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 37 0 0 0 10 0 0 10 10 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 0 0 0 46 10 0 0 0 0 37 0 0 0 0 0 % D
% Glu: 0 0 0 10 55 0 0 0 0 55 0 0 0 0 0 % E
% Phe: 0 100 100 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 37 0 0 0 0 0 0 0 91 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 19 19 0 0 0 % I
% Lys: 0 0 0 0 10 0 64 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 82 0 0 0 100 % L
% Met: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 46 0 0 0 0 0 37 10 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 46 0 10 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 19 0 0 0 0 0 0 100 0 % R
% Ser: 28 0 0 0 10 0 0 10 0 0 0 0 91 0 0 % S
% Thr: 0 0 0 0 0 46 19 73 0 0 0 19 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _