Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAP2 All Species: 26.36
Human Site: Y537 Identified Species: 58
UniProt: Q03519 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03519 NP_000535.3 686 75664 Y537 D E K P I S Q Y E H C Y L H S
Chimpanzee Pan troglodytes XP_509453 938 102525 Y745 D G K P I S A Y D H K Y L H R
Rhesus Macaque Macaca mulatta XP_001096136 907 99484 Y714 D G K P I S A Y D H K Y L H R
Dog Lupus familis XP_532099 791 86758 Y625 D G K P L W Q Y E H G Y L H R
Cat Felis silvestris
Mouse Mus musculus P36371 702 77426 Y536 D G E P L T E Y D H H Y L H R
Rat Rattus norvegicus P36372 703 77695 Y537 D G E P L V Q Y D H H Y L H R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus NP_001092827 701 75924 Y535 D G V P L R D Y E H R Y L H R
Frog Xenopus laevis NP_001085260 714 80692 Y538 D G K S L K E Y K H E Y L H S
Zebra Danio Brachydanio rerio Q56A55 714 77317 L539 D G L D I R T L D P S W L R G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_491754 815 90775 Y591 D G V P V R E Y D H K F L H T
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RY46 700 78020 L524 D G V P L K E L D V K W L R Q
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 34 34.5 68.6 N.A. 75.6 73.8 N.A. N.A. 49.3 41.7 30.6 N.A. N.A. N.A. 32.2 N.A.
Protein Similarity: 100 47.8 49.3 75.9 N.A. 84.7 83.2 N.A. N.A. 65.3 62.6 49.4 N.A. N.A. N.A. 50.1 N.A.
P-Site Identity: 100 66.6 66.6 66.6 N.A. 46.6 53.3 N.A. N.A. 53.3 53.3 20 N.A. N.A. N.A. 40 N.A.
P-Site Similarity: 100 73.3 73.3 73.3 N.A. 80 73.3 N.A. N.A. 60 73.3 33.3 N.A. N.A. N.A. 73.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.4 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 50.4 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 20 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 46.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 100 0 0 10 0 0 10 0 64 0 0 0 0 0 0 % D
% Glu: 0 10 19 0 0 0 37 0 28 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % F
% Gly: 0 91 0 0 0 0 0 0 0 0 10 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 82 19 0 0 82 0 % H
% Ile: 0 0 0 0 37 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 46 0 0 19 0 0 10 0 37 0 0 0 0 % K
% Leu: 0 0 10 0 55 0 0 19 0 0 0 0 100 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 82 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 28 0 0 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 28 0 0 0 0 10 0 0 19 55 % R
% Ser: 0 0 0 10 0 28 0 0 0 0 10 0 0 0 19 % S
% Thr: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 10 % T
% Val: 0 0 28 0 10 10 0 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 19 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 82 0 0 0 73 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _