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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EVX2
All Species:
14.55
Human Site:
Y286
Identified Species:
26.67
UniProt:
Q03828
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03828
NP_001073927.1
476
47800
Y286
H
S
H
V
P
L
H
Y
Y
P
H
V
G
V
T
Chimpanzee
Pan troglodytes
A2T756
283
30712
G103
P
A
G
P
F
P
E
G
A
E
P
G
V
L
E
Rhesus Macaque
Macaca mulatta
XP_001094253
475
47723
Y286
H
S
H
V
P
L
H
Y
Y
P
H
V
G
V
T
Dog
Lupus familis
XP_852353
476
47657
Y289
H
S
H
V
P
L
H
Y
Y
P
H
V
G
V
T
Cat
Felis silvestris
Mouse
Mus musculus
P49749
475
47884
Y289
H
S
H
V
P
L
H
Y
Y
P
H
V
G
V
T
Rat
Rattus norvegicus
P31246
372
40809
M192
V
W
F
Q
N
R
R
M
K
H
K
R
Q
T
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509846
426
44951
T245
A
A
L
N
L
P
E
T
T
I
K
V
W
F
Q
Chicken
Gallus gallus
Q08727
375
40980
H195
F
Q
N
R
R
M
K
H
K
R
Q
T
Q
C
K
Frog
Xenopus laevis
P50476
388
42004
P208
L
A
A
A
L
N
L
P
E
T
T
I
K
V
W
Zebra Danio
Brachydanio rerio
O42365
363
39796
N183
Q
V
K
V
W
F
Q
N
R
R
M
K
H
K
R
Tiger Blowfish
Takifugu rubipres
Q6IEI0
415
44026
R235
H
K
R
Q
T
H
H
R
D
G
S
G
G
G
N
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q93899
247
26800
Q67
Y
D
N
R
D
D
G
Q
M
R
R
Y
R
T
A
Sea Urchin
Strong. purpuratus
NP_999816
297
32819
S117
D
D
R
L
S
P
D
S
C
S
D
N
L
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.2
98.7
96
N.A.
94.3
22.6
N.A.
46.2
21.6
45.1
21.6
22.2
N.A.
N.A.
24.1
27.9
Protein Similarity:
100
28.7
99.1
96.8
N.A.
95.5
34.6
N.A.
56
33.4
59.4
32.9
36.1
N.A.
N.A.
32.5
36.1
P-Site Identity:
100
0
100
100
N.A.
100
0
N.A.
6.6
0
6.6
6.6
20
N.A.
N.A.
0
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
0
N.A.
13.3
20
20
6.6
20
N.A.
N.A.
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
8
8
0
0
0
0
8
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% C
% Asp:
8
16
0
0
8
8
8
0
8
0
8
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
16
0
8
8
0
0
0
8
8
% E
% Phe:
8
0
8
0
8
8
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
0
8
0
0
0
8
8
0
8
0
16
39
8
0
% G
% His:
39
0
31
0
0
8
39
8
0
8
31
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% I
% Lys:
0
8
8
0
0
0
8
0
16
0
16
8
8
8
8
% K
% Leu:
8
0
8
8
16
31
8
0
0
0
0
0
8
8
0
% L
% Met:
0
0
0
0
0
8
0
8
8
0
8
0
0
0
0
% M
% Asn:
0
0
16
8
8
8
0
8
0
0
0
8
0
0
8
% N
% Pro:
8
0
0
8
31
24
0
8
0
31
8
0
0
0
0
% P
% Gln:
8
8
0
16
0
0
8
8
0
0
8
0
16
0
16
% Q
% Arg:
0
0
16
16
8
8
8
8
8
24
8
8
8
0
8
% R
% Ser:
0
31
0
0
8
0
0
8
0
8
8
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
8
8
8
8
8
0
16
31
% T
% Val:
8
8
0
39
0
0
0
0
0
0
0
39
8
39
0
% V
% Trp:
0
8
0
0
8
0
0
0
0
0
0
0
8
0
8
% W
% Tyr:
8
0
0
0
0
0
0
31
31
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _