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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSF2
All Species:
8.18
Human Site:
S273
Identified Species:
18
UniProt:
Q03933
Number Species:
10
Phosphosite Substitution
Charge Score:
0.3
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03933
NP_001129036.1
536
60348
S273
E
T
N
E
D
V
I
S
D
P
S
N
C
S
Q
Chimpanzee
Pan troglodytes
XP_001155636
135
14602
Rhesus Macaque
Macaca mulatta
XP_001108944
517
58258
D257
D
V
T
D
D
N
A
D
E
E
N
I
P
V
I
Dog
Lupus familis
XP_533482
578
64802
S316
E
T
N
E
D
V
I
S
D
P
S
N
C
S
Q
Cat
Felis silvestris
Mouse
Mus musculus
P38533
535
60206
V273
E
T
N
E
D
V
V
V
D
S
S
N
Q
Y
P
Rat
Rattus norvegicus
NP_113882
513
57725
E253
I
I
I
Y
D
V
T
E
D
N
V
D
E
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P38530
564
62809
S293
E
T
N
E
D
T
T
S
D
S
S
N
C
S
R
Frog
Xenopus laevis
P41154
451
49454
V191
N
K
L
I
Q
F
L
V
S
L
V
Q
S
N
R
Zebra Danio
Brachydanio rerio
NP_571942
489
55522
G229
H
S
K
T
T
V
N
G
L
K
N
N
S
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22813
691
76915
L329
Q
S
V
E
D
L
L
L
Q
G
N
G
T
A
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96320
284
31309
D24
S
K
T
Y
Q
L
V
D
D
H
S
T
D
D
V
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.7
96.2
87
N.A.
94.5
91.2
N.A.
N.A.
76.4
35.8
52.6
N.A.
25.4
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
96.4
88.9
N.A.
96.4
93.4
N.A.
N.A.
84.5
53.5
67.3
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
100
N.A.
60
20
N.A.
N.A.
73.3
0
13.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
33.3
100
N.A.
66.6
26.6
N.A.
N.A.
80
20
26.6
N.A.
53.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% C
% Asp:
10
0
0
10
64
0
0
19
55
0
0
10
10
19
0
% D
% Glu:
37
0
0
46
0
0
0
10
10
10
0
0
10
10
0
% E
% Phe:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
10
0
10
0
10
0
0
10
% G
% His:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
10
10
10
10
0
0
19
0
0
0
0
10
0
0
19
% I
% Lys:
0
19
10
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
0
10
0
0
19
19
10
10
10
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
37
0
0
10
10
0
0
10
28
46
0
10
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
19
0
0
10
0
10
% P
% Gln:
10
0
0
0
19
0
0
0
10
0
0
10
10
0
19
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% R
% Ser:
10
19
0
0
0
0
0
28
10
19
46
0
19
28
0
% S
% Thr:
0
37
19
10
10
10
19
0
0
0
0
10
10
0
0
% T
% Val:
0
10
10
0
0
46
19
19
0
0
19
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
19
0
0
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _