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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSF2
All Species:
11.82
Human Site:
S366
Identified Species:
26
UniProt:
Q03933
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03933
NP_001129036.1
536
60348
S366
E
L
L
D
Y
L
D
S
I
D
C
S
L
E
D
Chimpanzee
Pan troglodytes
XP_001155636
135
14602
Rhesus Macaque
Macaca mulatta
XP_001108944
517
58258
L348
V
T
M
M
D
S
I
L
N
D
N
I
N
L
L
Dog
Lupus familis
XP_533482
578
64802
S409
E
L
L
D
Y
L
D
S
I
D
C
S
L
E
D
Cat
Felis silvestris
Mouse
Mus musculus
P38533
535
60206
S365
E
L
L
D
Y
L
D
S
I
D
C
S
L
E
D
Rat
Rattus norvegicus
NP_113882
513
57725
N344
T
M
M
D
S
I
L
N
D
N
I
N
L
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P38530
564
62809
L394
K
V
E
L
L
D
Y
L
D
S
I
D
C
S
L
Frog
Xenopus laevis
P41154
451
49454
T282
S
P
V
I
L
I
K
T
E
P
L
T
P
S
Q
Zebra Danio
Brachydanio rerio
NP_571942
489
55522
S320
L
N
K
P
S
C
L
S
L
E
D
P
M
K
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P22813
691
76915
Q439
K
A
Q
R
T
S
I
Q
H
S
T
Q
P
D
V
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q96320
284
31309
C115
I
A
S
T
A
G
K
C
V
V
V
G
S
P
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
22.7
96.2
87
N.A.
94.5
91.2
N.A.
N.A.
76.4
35.8
52.6
N.A.
25.4
N.A.
N.A.
N.A.
Protein Similarity:
100
24.2
96.4
88.9
N.A.
96.4
93.4
N.A.
N.A.
84.5
53.5
67.3
N.A.
45.1
N.A.
N.A.
N.A.
P-Site Identity:
100
0
6.6
100
N.A.
100
13.3
N.A.
N.A.
0
0
6.6
N.A.
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
0
13.3
100
N.A.
100
53.3
N.A.
N.A.
13.3
26.6
33.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
21
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
10
0
10
0
0
28
0
10
0
0
% C
% Asp:
0
0
0
37
10
10
28
0
19
37
10
10
0
10
28
% D
% Glu:
28
0
10
0
0
0
0
0
10
10
0
0
0
28
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
0
0
0
0
10
0
0
10
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
19
19
0
28
0
19
10
0
0
0
% I
% Lys:
19
0
10
0
0
0
19
0
0
0
0
0
0
10
0
% K
% Leu:
10
28
28
10
19
28
19
19
10
0
10
0
37
19
28
% L
% Met:
0
10
19
10
0
0
0
0
0
0
0
0
10
0
0
% M
% Asn:
0
10
0
0
0
0
0
10
10
10
10
10
10
0
0
% N
% Pro:
0
10
0
10
0
0
0
0
0
10
0
10
19
10
0
% P
% Gln:
0
0
10
0
0
0
0
10
0
0
0
10
0
0
10
% Q
% Arg:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
10
0
19
19
0
37
0
19
0
28
10
19
10
% S
% Thr:
10
10
0
10
10
0
0
10
0
0
10
10
0
0
0
% T
% Val:
10
10
10
0
0
0
0
0
10
10
10
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
28
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _